Abstract
Transforming growth factor (TGF)beta is increased in asthma and may suppress immune responses. It is unknown whether TGF-beta activity may impact on rhinovirus infections and play a role in virus-associated asthma exacerbations. TGF-beta mediates enhanced rhinovirus replication probably probably via its suppressive actions on host type 1 interferon responses.
Original language | English |
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Pages (from-to) | 339 - 347 |
Number of pages | 9 |
Journal | American Journal of Respiratory Cell and Molecular Biology |
Volume | 41 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2009 |