Transforming growth factor (TGF)beta is increased in asthma and may suppress immune responses. It is unknown whether TGF-beta activity may impact on rhinovirus infections and play a role in virus-associated asthma exacerbations. TGF-beta mediates enhanced rhinovirus replication probably probably via its suppressive actions on host type 1 interferon responses.
|Pages (from-to)||339 - 347|
|Number of pages||9|
|Journal||American Journal of Respiratory Cell and Molecular Biology|
|Publication status||Published - 2009|