Transferring preterm infants from incubators to open cots at 1600g: a multicentre randomized trial

To determine the effects on weight gain and temperature control of transferring preterm infants from incubators to open cots at a weight of 1600 g versus a weight of 1800 g. Design: Randomised controlled trial. Setting: One tertiary and two regional neonatal units in public hospitals in Queensland, Australia. Participants: 182 preterm infants born with a birth weight less than 1600 g, who were at least 48 h old; had not required ventilation or continuous positive airways pressure within the last 48 h; were medically stable with no oxygen requirement, or significant apnoea or bradycardia; did not require phototherapy; and were enterally fed with an intake (breast milk/formula) of at least 60 ml/kg/day. Interventions: Transfer into an open cot at 1600 or 1800 g. Main outcome measures: The primary outcomes were temperature stability and average daily weight gain over the first 14 days following transfer to an open cot. Results: 90 infants in the 1600 g group and 92 infants in the 1800 g group were included in the analysis. Over the first 72 h, more infants in the 1800 g group had temperatures 37.1?C (p=0.02). Average daily weight gain in the 1600 g group was 17.07 (SD?4.5) g/kg/day and in the 1800 g group, 13.97 (SD?4.7) g/kg/day (p=