Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

Sivan Dahan; Stuart Knutton; Robert K. Shaw; Valerie F. Crepin; Gordon Dougan; Gad Frankel

doi:10.1128/IAI.72.9.5452-5459.2004

Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

Sivan Dahan, Stuart Knutton, Robert K. Shaw, Valerie F. Crepin, Gordon Dougan, Gad Frankel

Research output: Contribution to journal › Article › Research › peer-review

69 Citations (Scopus)

Abstract

Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.

Original language	English
Pages (from-to)	5452-5459
Number of pages	8
Journal	Infection and Immunity
Volume	72
Issue number	9
DOIs	https://doi.org/10.1128/IAI.72.9.5452-5459.2004
Publication status	Published - 1 Sept 2004
Externally published	Yes

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10.1128/IAI.72.9.5452-5459.2004

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title = "Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes",

abstract = "Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.",

author = "Sivan Dahan and Stuart Knutton and Shaw, \{Robert K.\} and Crepin, \{Valerie F.\} and Gordon Dougan and Gad Frankel",

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AU - Dahan, Sivan

AU - Knutton, Stuart

AU - Shaw, Robert K.

AU - Crepin, Valerie F.

AU - Dougan, Gordon

AU - Frankel, Gad

PY - 2004/9/1

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N2 - Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.

AB - Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.

UR - https://www.scopus.com/pages/publications/4544220703

U2 - 10.1128/IAI.72.9.5452-5459.2004

DO - 10.1128/IAI.72.9.5452-5459.2004

M3 - Article

C2 - 15322044

AN - SCOPUS:4544220703

SN - 0019-9567

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EP - 5459

JO - Infection and Immunity

JF - Infection and Immunity

IS - 9

ER -

Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

Abstract

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