Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

Sivan Dahan, Stuart Knutton, Robert K. Shaw, Valerie F. Crepin, Gordon Dougan, Gad Frankel

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

Abstract

Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.

Original languageEnglish
Pages (from-to)5452-5459
Number of pages8
JournalInfection and Immunity
Volume72
Issue number9
DOIs
Publication statusPublished - 1 Sep 2004
Externally publishedYes

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