Abstract
The clinical success of cisplatin continues to inspire the development of metal-based anticancer drug candidates. This article is meant to present the current state-of-the-art and science of ruthenium(II)- and rhenium(I)-based anticancer drug candidates born out of our work in this field. Our recent efforts to elicit photoactivation of intact (organo)metallic anticancer drug candidates as a promising way for commanding their activity within cancer cells are also briefly summarized. 1 Introduction 2 Ruthenium(II) Complexes 3 Rhenium(I) Complexes 4 Concluding Remarks
Original language | English |
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Pages (from-to) | 275-284 |
Number of pages | 10 |
Journal | Synlett |
Volume | 26 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2015 |
Keywords
- antitumor agents,
- carbonyl complexes
- drugs
- medicinal chemistry
- ruthenium
- photochemistry