Towards the synthesis of prevezol C: total enantioselective synthesis of (-)-2-epi-prevezol C

Michael Blair; Craig Macdonald Forsyth; Kellie Louise Tuck

doi:10.1016/j.tetlet.2010.07.019

Towards the synthesis of prevezol C: total enantioselective synthesis of (-)-2-epi-prevezol C

Michael Blair, Craig Macdonald Forsyth, Kellie Louise Tuck

School of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

7 Citations (Scopus)

Abstract

(-)-2-epi-Prevezol C was readily accessed from the chirons (-)- and (+)-limonene oxide in a total of nine steps and in 24 yield. This efficient enantioselective synthesis of this complex product utilises a highly stereoconvergent, substrate-controlled allylic alkylation strategy to assemble rapidly the unprecedented diterpene core.

Original language	English
Pages (from-to)	4808 - 4811
Number of pages	4
Journal	Tetrahedron Letters
Volume	51
Issue number	37
DOIs	https://doi.org/10.1016/j.tetlet.2010.07.019
Publication status	Published - 2010

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title = "Towards the synthesis of prevezol C: total enantioselective synthesis of (-)-2-epi-prevezol C",

abstract = "(-)-2-epi-Prevezol C was readily accessed from the chirons (-)- and (+)-limonene oxide in a total of nine steps and in 24 yield. This efficient enantioselective synthesis of this complex product utilises a highly stereoconvergent, substrate-controlled allylic alkylation strategy to assemble rapidly the unprecedented diterpene core.",

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AU - Forsyth, Craig Macdonald

AU - Tuck, Kellie Louise

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Y1 - 2010

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AB - (-)-2-epi-Prevezol C was readily accessed from the chirons (-)- and (+)-limonene oxide in a total of nine steps and in 24 yield. This efficient enantioselective synthesis of this complex product utilises a highly stereoconvergent, substrate-controlled allylic alkylation strategy to assemble rapidly the unprecedented diterpene core.

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DO - 10.1016/j.tetlet.2010.07.019

M3 - Article

VL - 51

SP - 4808

EP - 4811

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 37

ER -

Towards the synthesis of prevezol C: total enantioselective synthesis of (-)-2-epi-prevezol C

Abstract

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