Towards the synthesis of prevezol C: total enantioselective synthesis of (-)-2-epi-prevezol C

Michael Blair, Craig Macdonald Forsyth, Kellie Louise Tuck

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(-)-2-epi-Prevezol C was readily accessed from the chirons (-)- and (+)-limonene oxide in a total of nine steps and in 24 yield. This efficient enantioselective synthesis of this complex product utilises a highly stereoconvergent, substrate-controlled allylic alkylation strategy to assemble rapidly the unprecedented diterpene core.
Original languageEnglish
Pages (from-to)4808 - 4811
Number of pages4
JournalTetrahedron Letters
Issue number37
Publication statusPublished - 2010

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