TY - JOUR
T1 - Towards building a more complex view of the lateral geniculate nucleus
T2 - Recent advances in understanding its role
AU - Ghodrati, Masoud
AU - Khaligh-Razavi, Seyed Mahdi
AU - Lehky, Sidney R.
PY - 2017/9/1
Y1 - 2017/9/1
N2 - The lateral geniculate nucleus (LGN) has often been treated in the past as a linear filter that adds little to retinal processing of visual inputs. Here we review anatomical, neurophysiological, brain imaging, and modeling studies that have in recent years built up a much more complex view of LGN. These include effects related to nonlinear dendritic processing, cortical feedback, synchrony and oscillations across LGN populations, as well as involvement of LGN in higher level cognitive processing. Although recent studies have provided valuable insights into early visual processing including the role of LGN, a unified model of LGN responses to real-world objects has not yet been developed. In the light of recent data, we suggest that the role of LGN deserves more careful consideration in developing models of high-level visual processing.
AB - The lateral geniculate nucleus (LGN) has often been treated in the past as a linear filter that adds little to retinal processing of visual inputs. Here we review anatomical, neurophysiological, brain imaging, and modeling studies that have in recent years built up a much more complex view of LGN. These include effects related to nonlinear dendritic processing, cortical feedback, synchrony and oscillations across LGN populations, as well as involvement of LGN in higher level cognitive processing. Although recent studies have provided valuable insights into early visual processing including the role of LGN, a unified model of LGN responses to real-world objects has not yet been developed. In the light of recent data, we suggest that the role of LGN deserves more careful consideration in developing models of high-level visual processing.
UR - http://www.scopus.com/inward/record.url?scp=85021854065&partnerID=8YFLogxK
U2 - 10.1016/j.pneurobio.2017.06.002
DO - 10.1016/j.pneurobio.2017.06.002
M3 - Review Article
AN - SCOPUS:85021854065
SN - 0301-0082
VL - 156
SP - 214
EP - 255
JO - Progress in Neurobiology
JF - Progress in Neurobiology
ER -