Towards an HIV cure: a global scientific strategy

Steven G Deeks, Brigitte Autran, Ben Berkhout, Monsef Benkirane, Scott Cairns, Nicolas Chomont, Tae Wook Chun, Melissa Churchill, Michele Di Mascio, Christine Katlama, Alain Lafeuillade, Alan Landay, Michael M Lederman, Sharon R Lewin, Frank Maldarelli, David M Margolis, Martin M Markowitz, Javier Martinez-Picado, James Mullins, John W Mellors & 16 others Santiago Moreno, Una M O'Doherty, Sarah Palmer, Marie Capucine Penicaud, Matija B Peterlin, Guido Poli, Jean Pierre Routy, Christine Rouzioux, Guido Silvestri, Mario Stevenson, Amalio Telenti, Carine Van Lint, Eric Verdin, Anne Woolfrey, John A Zaia, Francoise Barre-Sinoussi

Research output: Contribution to journalArticleResearchpeer-review

355 Citations (Scopus)

Abstract

Given the limitations of antiretroviral therapy and recent advances in our understanding of HIV persistence during effective treatment, there is a growing recognition that a cure for HIV infection is both needed and feasible. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. Several priorities for basic, translational and clinical research were identified. This Opinion article summarizes the group s recommended key goals for the international community. ? 2012 Macmillan Publishers Limited. All rights reserved.
Original languageEnglish
Pages (from-to)607 - 614
Number of pages8
JournalNature Reviews Immunology
Volume12
Issue number8
DOIs
Publication statusPublished - 2012

Cite this

Deeks, S. G., Autran, B., Berkhout, B., Benkirane, M., Cairns, S., Chomont, N., ... Barre-Sinoussi, F. (2012). Towards an HIV cure: a global scientific strategy. Nature Reviews Immunology, 12(8), 607 - 614. https://doi.org/10.1038/nri3262
Deeks, Steven G ; Autran, Brigitte ; Berkhout, Ben ; Benkirane, Monsef ; Cairns, Scott ; Chomont, Nicolas ; Chun, Tae Wook ; Churchill, Melissa ; Di Mascio, Michele ; Katlama, Christine ; Lafeuillade, Alain ; Landay, Alan ; Lederman, Michael M ; Lewin, Sharon R ; Maldarelli, Frank ; Margolis, David M ; Markowitz, Martin M ; Martinez-Picado, Javier ; Mullins, James ; Mellors, John W ; Moreno, Santiago ; O'Doherty, Una M ; Palmer, Sarah ; Penicaud, Marie Capucine ; Peterlin, Matija B ; Poli, Guido ; Routy, Jean Pierre ; Rouzioux, Christine ; Silvestri, Guido ; Stevenson, Mario ; Telenti, Amalio ; Van Lint, Carine ; Verdin, Eric ; Woolfrey, Anne ; Zaia, John A ; Barre-Sinoussi, Francoise. / Towards an HIV cure: a global scientific strategy. In: Nature Reviews Immunology. 2012 ; Vol. 12, No. 8. pp. 607 - 614.
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Deeks, SG, Autran, B, Berkhout, B, Benkirane, M, Cairns, S, Chomont, N, Chun, TW, Churchill, M, Di Mascio, M, Katlama, C, Lafeuillade, A, Landay, A, Lederman, MM, Lewin, SR, Maldarelli, F, Margolis, DM, Markowitz, MM, Martinez-Picado, J, Mullins, J, Mellors, JW, Moreno, S, O'Doherty, UM, Palmer, S, Penicaud, MC, Peterlin, MB, Poli, G, Routy, JP, Rouzioux, C, Silvestri, G, Stevenson, M, Telenti, A, Van Lint, C, Verdin, E, Woolfrey, A, Zaia, JA & Barre-Sinoussi, F 2012, 'Towards an HIV cure: a global scientific strategy', Nature Reviews Immunology, vol. 12, no. 8, pp. 607 - 614. https://doi.org/10.1038/nri3262

Towards an HIV cure: a global scientific strategy. / Deeks, Steven G; Autran, Brigitte; Berkhout, Ben; Benkirane, Monsef; Cairns, Scott; Chomont, Nicolas; Chun, Tae Wook; Churchill, Melissa; Di Mascio, Michele; Katlama, Christine; Lafeuillade, Alain; Landay, Alan; Lederman, Michael M; Lewin, Sharon R; Maldarelli, Frank; Margolis, David M; Markowitz, Martin M; Martinez-Picado, Javier; Mullins, James; Mellors, John W; Moreno, Santiago; O'Doherty, Una M; Palmer, Sarah; Penicaud, Marie Capucine; Peterlin, Matija B; Poli, Guido; Routy, Jean Pierre; Rouzioux, Christine; Silvestri, Guido; Stevenson, Mario; Telenti, Amalio; Van Lint, Carine; Verdin, Eric; Woolfrey, Anne; Zaia, John A; Barre-Sinoussi, Francoise.

In: Nature Reviews Immunology, Vol. 12, No. 8, 2012, p. 607 - 614.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Autran, Brigitte

AU - Berkhout, Ben

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AU - Chomont, Nicolas

AU - Chun, Tae Wook

AU - Churchill, Melissa

AU - Di Mascio, Michele

AU - Katlama, Christine

AU - Lafeuillade, Alain

AU - Landay, Alan

AU - Lederman, Michael M

AU - Lewin, Sharon R

AU - Maldarelli, Frank

AU - Margolis, David M

AU - Markowitz, Martin M

AU - Martinez-Picado, Javier

AU - Mullins, James

AU - Mellors, John W

AU - Moreno, Santiago

AU - O'Doherty, Una M

AU - Palmer, Sarah

AU - Penicaud, Marie Capucine

AU - Peterlin, Matija B

AU - Poli, Guido

AU - Routy, Jean Pierre

AU - Rouzioux, Christine

AU - Silvestri, Guido

AU - Stevenson, Mario

AU - Telenti, Amalio

AU - Van Lint, Carine

AU - Verdin, Eric

AU - Woolfrey, Anne

AU - Zaia, John A

AU - Barre-Sinoussi, Francoise

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AB - Given the limitations of antiretroviral therapy and recent advances in our understanding of HIV persistence during effective treatment, there is a growing recognition that a cure for HIV infection is both needed and feasible. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. Several priorities for basic, translational and clinical research were identified. This Opinion article summarizes the group s recommended key goals for the international community. ? 2012 Macmillan Publishers Limited. All rights reserved.

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Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N et al. Towards an HIV cure: a global scientific strategy. Nature Reviews Immunology. 2012;12(8):607 - 614. https://doi.org/10.1038/nri3262