TY - JOUR
T1 - Towards a structural understanding of the anti-ulcer and anti-gastritis drug bismuth subsalicylate
AU - Andrews, Philip Craig
AU - Deacon, Glen Berenger
AU - Forsyth, Craig Macdonald
AU - Junk, Peter Courtney
AU - Kumar, Ish
AU - Maguire, Melissa
PY - 2006/9/2
Y1 - 2006/9/2
N2 - The action of Pepto-Bismol arising from the structure and hydrolysis of bismuth subsalicylate (BSS) is not yet understood. Two bismuth oxosalicylate clusters, [Bi38O44(HSal)26(Me 2CO)16(H2O)2] (1) and [Bi 9O7(HSal)13(Me2CO)5] (2), have been characterized which provide structural insight into the nature of BSS. A Bi9O7 cluster forms the core of 2 and is found at the heart of 1 (see picture; core Bi atoms: green, core O atoms: red). (Figure Presented).
AB - The action of Pepto-Bismol arising from the structure and hydrolysis of bismuth subsalicylate (BSS) is not yet understood. Two bismuth oxosalicylate clusters, [Bi38O44(HSal)26(Me 2CO)16(H2O)2] (1) and [Bi 9O7(HSal)13(Me2CO)5] (2), have been characterized which provide structural insight into the nature of BSS. A Bi9O7 cluster forms the core of 2 and is found at the heart of 1 (see picture; core Bi atoms: green, core O atoms: red). (Figure Presented).
KW - Bismuth
KW - Bismuth oxide
KW - Oxo ligands
KW - Salicylate ligands
KW - Solid-state structures
UR - http://www.scopus.com/inward/record.url?scp=84980436590&partnerID=8YFLogxK
U2 - 10.1002/anie.200600469
DO - 10.1002/anie.200600469
M3 - Article
C2 - 16865763
SN - 1433-7851
VL - 45
SP - 5638
EP - 5642
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 34
ER -