Total hip replacement: a systematic review and meta-analysis on mid-term quality of life

Leonard Shan, Bernard Liyang Shan, David Graham, Akshat Saxena

Research output: Contribution to journalArticleOther

116 Citations (Scopus)


Objective: Total hip replacement (THR) is one of the most successful and frequently performed operations worldwide. Health-related quality of life (HRQOL) is a key outcome measure of surgery. We investigated mid-term HRQOL after THR in patients with osteoarthritis (OA). Design: A systematic review of clinical studies published after January 2000 was performed using strict eligibility criteria. Quality appraisal and data tabulation were performed using pre-determined forms. Data were synthesised by narrative review and random-effects meta-analysis using standardised response means. Tau2 and I2 values and Funnel plots were analysed. Results: 20 studies were included. Mid-term post-operative HRQOL is superior compared to pre-operative status on qualitative and quantitative analysis. Pooled response means of total Harris Hip Score (HHS) (P
Original languageEnglish
Pages (from-to)389 - 406
Number of pages18
JournalOsteoarthritis and Cartilage
Issue number3
Publication statusPublished - 2014

Cite this