Abstract
Purpose: To investigate whether subclinical ciliochoroidal effusion and resulting asymptomatic angle narrowing occurs in patients taking topiramate, by ultrasound biomicroscopy (UBM).Methods: Chinese patients aged 18-75 years for whom topiramate was indicated were recruited. Examinations including UBM were performed before and 4 weeks after commencement of topiramate.Results: In this pilot of 20 eyes of 20 patients, there were no statistically significant changes in the angle parameters noted on gonioscopy or UBM, including anterior chamber depth, angle-opening distance at 500 m, trabecular ciliary process distance, trabecular-iris angle, and scleral thickness.Conclusion: Short-term use of topiramate does not induce asymptomatic angle narrowing.
Original language | English |
---|---|
Pages (from-to) | 2079-2081 |
Number of pages | 3 |
Journal | Eye |
Volume | 23 |
Issue number | 11 |
DOIs | |
Publication status | Published - 1 Jan 2009 |
Externally published | Yes |
Keywords
- Acute angle-closure glaucoma
- Topiramate
- Ultrasound biomicroscopy