Toe-brachial index and toe systolic blood pressure for the diagnosis of peripheral arterial disease (Protocol)

Peta E. Tehan, Joseph L. Mills, Mathew Sebastian, Christopher Oldmeadow, Vivienne Chuter

Research output: Contribution to journalArticleResearchpeer-review


Objectives: This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:. To (1) estimate the accuracy of TSBP and TBI for the diagnosis of PAD in the lower extremities at different cut-off values for test positivity in populations at risk of PAD, and (2) compare the accuracy of TBI and TSBP for the diagnosis of PAD in the lower extremities. Secondary objectives To investigate several possible sources of heterogeneity in test accuracy, including the following: patient group tested (people with type 1 or type 2 diabetes, people with renal disease and general population), type of equipment used, positivity threshold and type of reference standard.

Original languageEnglish
Article numberCD013783
Number of pages14
JournalCochrane Database of Systematic Reviews
Issue number11
Publication statusPublished - 17 Nov 2020
Externally publishedYes

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