To address emerging infections, we must invest in enduring systems: the kinetics and dynamics of health systems strengthening

S. Pastakia, B. Njuguna, P. V. Le, M. K. Singh, T. P. Brock

Research output: Contribution to journalReview ArticleOtherpeer-review

2 Citations (Scopus)


Clinical pharmacology uses foundational principles of pharmacokinetics (PK) and pharmacodynamics (PD) to address medication use spanning a continuum from molecules to the masses. In the realm of infectious diseases, PK/PD attributes are considered especially important, because subtherapeutic dosing of antibiotics has been associated with poorer clinical outcomes in patients and increased incidences of drug resistance in populations. In consideration of these PK/PD principles, we will describe the analogous relationship between health systems strengthening, including for educating healthcare providers about emerging infections, and the tenets of therapeutic drug monitoring.

Original languageEnglish
Pages (from-to)362-364
Number of pages3
JournalClinical Pharmacology & Therapeutics
Issue number4
Publication statusPublished - 1 Oct 2015
Externally publishedYes

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