TMS-EEG: A technique that has come of age?

Abstract Researchers are continuing to make efforts to combine Transcranial magnetic stimulation (TMS) with EEG as a potential technique for clinical and cognitive neuroscience applications. The development of this capacity will allow more detailed exploration of the effects of TMS on the brain and facilitate the development of this as a potentially useful tool for investigating cortical excitability and cortical connectivity. The combination of TMS and EEG will also allow for the study of the effects of sub motor threshold stimulation in motor cortex and other brain regions. Continued research has suggested that more commonly available hardware will be able to be used for similar activities, opening up the use of TMS EEG much more widely. One such approach involves the use of modern direct current (DC) amplifiers that allow EEG recording at high acquisition rates or the use of amplifiers with high dynamic range.