TY - JOUR
T1 - Time course of EEG slow-wave activity in pre-school children with sleep disordered breathing: a possible mechanism for daytime deficits?
AU - Biggs, Sarah Nichole
AU - Walter, Lisa Mary
AU - Nisbet, Lauren
AU - Jackman, Angela Ranee
AU - Anderson, Vicki Anne
AU - Nixon, Gillian Michelle
AU - Davey, Margot J
AU - Trinder, John A
AU - Hoffmann, Robert
AU - Armitage, Roseanne
AU - Horne, Rosemary Sylvia Claire
PY - 2012
Y1 - 2012
N2 - Daytime deficits in children with sleep disordered breathing (SDB) are theorized to result from hypoxic insult to the developing brain or fragmented sleep. Yet, these do not explain why deficits occur in primary snorers (PS). The time course of slow wave EEG activity (SWA), a proxy of homeostatic regulation and cortical maturation, may provide insight. METHODS: Clinical and control subjects (N=175: mean age 4.3+/-0.9y: 61 male) participated in overnight polysomnography (PSG). Standard sleep scoring and power spectral analyses were conducted on EEG (C4/A1; 0.5-5 events/h). Group differences were found in the percentage of time spent in NREM Stages 1 and 4 (p
AB - Daytime deficits in children with sleep disordered breathing (SDB) are theorized to result from hypoxic insult to the developing brain or fragmented sleep. Yet, these do not explain why deficits occur in primary snorers (PS). The time course of slow wave EEG activity (SWA), a proxy of homeostatic regulation and cortical maturation, may provide insight. METHODS: Clinical and control subjects (N=175: mean age 4.3+/-0.9y: 61 male) participated in overnight polysomnography (PSG). Standard sleep scoring and power spectral analyses were conducted on EEG (C4/A1; 0.5-5 events/h). Group differences were found in the percentage of time spent in NREM Stages 1 and 4 (p
UR - http://www.sciencedirect.com/science/article/pii/S1389945712002237
U2 - 10.1016/j.sleep.2012.05.006
DO - 10.1016/j.sleep.2012.05.006
M3 - Article
VL - 13
SP - 999
EP - 1005
JO - Sleep Medicine
JF - Sleep Medicine
SN - 1389-9457
IS - 8
ER -