Thymic regulatory T cell development: role of signalling pathways and transcription factors

Mark Engel, Tom Sidwell, Ajithkumar Vasanthakumar, George Grigoriadis, Ashish Banerjee

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Abstract

Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.
Original languageEnglish
Pages (from-to)1 - 9
Number of pages9
JournalClinical and Developmental Immunology
Volume2013
Issue numberArt # e617585
DOIs
Publication statusPublished - 2013

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