TY - JOUR
T1 - Three-dimensional dual-phase whole-heart MR imaging
T2 - Clinical implications for congenital heart disease
AU - Hussain, Tarique
AU - Lossnitzer, Dirk
AU - Bellsham-Revell, Hannah
AU - Valverde, Israel
AU - Beerbaum, Philipp
AU - Razavi, Reza
AU - Bell, Aaron J.
AU - Schaeffter, Tobias
AU - Botnar, Rene M.
AU - Uribe, Sergio A.
AU - Greil, Gerald F.
PY - 2012
Y1 - 2012
N2 - Purpose: To identify which rest phase (systolic or diastolic) is optimum for assessing or measuring cardiac structures in the setting of three-dimensional (3D) whole-heart imaging in congenital heart disease (CHD). Materials and Methods: The study was approved by the institutional review board; informed consent was obtained. Fifty children (26 male and 24 female patients) underwent 3D dual-phase wholeheart imaging. Cardiac structures were analyzed for contrast-to-noise ratio (CNR) and image quality. Cross-sectional measurements were taken of the aortic arch, right ventricular (RV) outflow tract (RVOT) and pulmonary arteries. Normally distributed variables were compared by using paired t tests, and categorical data were compared by using Wilcoxon signed-rank test. Results: Mean CNR and image quality were significantly (all P < .05) greater in systole for the right atrium (CNR, 8.9 vs 7.5; image quality, 438 vs 91), left atrium (CNR, 8.0 vs 5.3; image quality, 1006 vs 29), RV (CNR, 10.6 vs 8.2; image quality, 131 vs 23), LV (CNR, 9.4 vs 7.7; image quality, 125 vs 28), and pulmonary veins (CNR, 6.2 vs 4.9; image quality, 914 vs 32). Conversely, diastolic CNR was significantly higher in the aorta (9.2 vs 8.2; P = .013) and diastolic image quality was higher for the left pulmonary artery (238 vs 62; P = .007), right pulmonary artery (219 vs 35; P < .001), and for imaging of an area after an arterial stenosis (164 vs 7; P < .001). All aortic arch and RVOT cross-sectional measurements were significantly (P < .05) greater in systole (narrowest point of arch, 70 vs 53 mm 2; descending aorta, 71 vs 58 mm 2; transverse arch, 293 vs 275 mm 2; valvar RVOT, 291 vs 268 mm 2; supravalvar RVOT, 337 vs 280 mm 2; prebifurcation RVOT, 329 vs 259 mm 2). Conclusion: Certain structures in CHD are better imaged in systole and others in diastole, and therefore, the dual-phase approach allows a higher overall success rate. This approach also allows depiction of diameter changes between systole and diastole and is therefore preferable to standard single-phase sequences for the planning of interventional procedures.
AB - Purpose: To identify which rest phase (systolic or diastolic) is optimum for assessing or measuring cardiac structures in the setting of three-dimensional (3D) whole-heart imaging in congenital heart disease (CHD). Materials and Methods: The study was approved by the institutional review board; informed consent was obtained. Fifty children (26 male and 24 female patients) underwent 3D dual-phase wholeheart imaging. Cardiac structures were analyzed for contrast-to-noise ratio (CNR) and image quality. Cross-sectional measurements were taken of the aortic arch, right ventricular (RV) outflow tract (RVOT) and pulmonary arteries. Normally distributed variables were compared by using paired t tests, and categorical data were compared by using Wilcoxon signed-rank test. Results: Mean CNR and image quality were significantly (all P < .05) greater in systole for the right atrium (CNR, 8.9 vs 7.5; image quality, 438 vs 91), left atrium (CNR, 8.0 vs 5.3; image quality, 1006 vs 29), RV (CNR, 10.6 vs 8.2; image quality, 131 vs 23), LV (CNR, 9.4 vs 7.7; image quality, 125 vs 28), and pulmonary veins (CNR, 6.2 vs 4.9; image quality, 914 vs 32). Conversely, diastolic CNR was significantly higher in the aorta (9.2 vs 8.2; P = .013) and diastolic image quality was higher for the left pulmonary artery (238 vs 62; P = .007), right pulmonary artery (219 vs 35; P < .001), and for imaging of an area after an arterial stenosis (164 vs 7; P < .001). All aortic arch and RVOT cross-sectional measurements were significantly (P < .05) greater in systole (narrowest point of arch, 70 vs 53 mm 2; descending aorta, 71 vs 58 mm 2; transverse arch, 293 vs 275 mm 2; valvar RVOT, 291 vs 268 mm 2; supravalvar RVOT, 337 vs 280 mm 2; prebifurcation RVOT, 329 vs 259 mm 2). Conclusion: Certain structures in CHD are better imaged in systole and others in diastole, and therefore, the dual-phase approach allows a higher overall success rate. This approach also allows depiction of diameter changes between systole and diastole and is therefore preferable to standard single-phase sequences for the planning of interventional procedures.
UR - http://www.scopus.com/inward/record.url?scp=84862500949&partnerID=8YFLogxK
U2 - 10.1148/radiol.12111700
DO - 10.1148/radiol.12111700
M3 - Article
C2 - 22517963
AN - SCOPUS:84862500949
SN - 0033-8419
VL - 263
SP - 547
EP - 554
JO - Radiology
JF - Radiology
IS - 2
ER -