Thread as a substrate for low-cost point-of-care diagnostics

X. Li, D. Ballerini, J. Tian, W. Shen

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Abstract

This study presents new applications of thread-based microfluidic systems in chemical and biochemical diagnostics. Our recent reports have demonstrated the capability of fabricating low-cost microfluidic devices using ubiquitous multifilament materials such as threads. The gaps between fibres in threads provide capillary wicking channels for liquid transport; therefore, liquid can penetrate along threads without the need of external forces. The new threadbased system, combined with the cheap dosing tools, is capable of easily and rapidly semi-quantifying the concentration of analytes in human body fluids. The utility of this system is further extended for the rapid and easy blood grouping with only small amount of whole blood (~ 2 μL for ABO blood typing), which is an essential test before blood transfusion. These low-cost and portable microfluidic devices are easy to fabricate, simple to use, and do not require powers such as electricity; thus providing a desirable analytical platform for point-of-care applications.

Original languageEnglish
Title of host publicationSustainable Chemistry 2011: 1st International Conference on Sustainable Chemistry
Subtitle of host publicationAntwerp, Belgium; 6 July 2011 through 8 July 2011
EditorsG. Reniers, C.A. Brebbia
Place of PublicationSouthampton UK
PublisherWITPress
Pages233-244
Number of pages12
ISBN (Print)9781845645588
DOIs
Publication statusPublished - 2011
EventInternational Conference on Sustainable Chemistry (CHEM 2011) - Antwerp, Belgium
Duration: 6 Jul 20118 Jul 2011
Conference number: 1st
http://www.wessex.ac.uk/conferences/2011/sustainablechemistry-2011

Publication series

NameWIT Transactions on Ecology and the Environment
PublisherWITPress
Volume154
ISSN (Print)1746-448x
ISSN (Electronic)1743-3541

Conference

ConferenceInternational Conference on Sustainable Chemistry (CHEM 2011)
CountryBelgium
CityAntwerp
Period6/07/118/07/11
Internet address

Keywords

  • Low-cost diagnostics
  • Microfluidic
  • Point-of-care
  • Thread-based

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