TY - JOUR
T1 - Thiols as an efficient hydrogen atom donor in free radical transformations in aqueous media
AU - Lykakis, I
AU - Perchyonok, Victoria
PY - 2010
Y1 - 2010
N2 - This paper highlights several methods of C-C and C-H transfer reactions in aqueous media. In all cases, thiols
play the role of the reducing agents. A variety of useful synthetic methodologies were also described, which occurred
mainly via a free radical non-chain transfer processes. The potential usefulness of free radical reactions in water is demonstrated
by ever-increasing studies over the last 5 years. In addition, a cis-trans lipid isomerization process under photoand
gamma-irradiation conditions was reported. The complexity of the selective generation of thiyl radical in aqueous
media and/or in biological milieus makes this topic highly important in chemistry, biology and medicine.
AB - This paper highlights several methods of C-C and C-H transfer reactions in aqueous media. In all cases, thiols
play the role of the reducing agents. A variety of useful synthetic methodologies were also described, which occurred
mainly via a free radical non-chain transfer processes. The potential usefulness of free radical reactions in water is demonstrated
by ever-increasing studies over the last 5 years. In addition, a cis-trans lipid isomerization process under photoand
gamma-irradiation conditions was reported. The complexity of the selective generation of thiyl radical in aqueous
media and/or in biological milieus makes this topic highly important in chemistry, biology and medicine.
UR - http://www.ingentaconnect.com/content/ben/coc/2010/00000014/00000010/art00005
U2 - 10.2174/138527210791130523
DO - 10.2174/138527210791130523
M3 - Article
SN - 1385-2728
VL - 14
SP - 1075
EP - 1082
JO - Current Organic Chemistry
JF - Current Organic Chemistry
IS - 10
ER -