Thermoresponsive nanohybrids for tumor imaging

Harini Hapuarachchi, Malin Premaratne

Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

Abstract

We demonstrate the prospect of using thermoresponsive polymer capped gold nanosphere-cadmium telluride quantum dot (QD) nanohybrids for minimally invasive detection of cancerous tissue and for feedback control of tumor temperature in localized hyperthermia therapy conducted using gold nanorods, to minimize damage to the surrounding healthy tissue. Here, we use a generalized nonlocal optical response method based cavity quantum electrodynamical formalism and show that the enhancement of the Rayleigh scattering intensity of the nanohybrid over that of the isolated gold nanosphere follows an exponential scaling with varying nanohybrid centre separation distance, in the close vicinity of the QD resonance frequency, which makes them ideal candidates for a multitude of distance based sensing applications.

Original languageEnglish
Title of host publicationProceedings of the 12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages20-24
Number of pages5
ISBN (Electronic)9781538675786
DOIs
Publication statusPublished - 13 Feb 2019
EventIEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED) 2018 - Waikiki Beach, United States
Duration: 2 Dec 20185 Dec 2018
Conference number: 12th

Publication series

NameIEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED
Volume2018-December
ISSN (Print)2159-6964
ISSN (Electronic)2159-6972

Conference

ConferenceIEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED) 2018
Abbreviated titleNANOMED 2018
CountryUnited States
CityWaikiki Beach
Period2/12/185/12/18

Cite this

Hapuarachchi, H., & Premaratne, M. (2019). Thermoresponsive nanohybrids for tumor imaging. In Proceedings of the 12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018 (pp. 20-24). [8641671] (IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED; Vol. 2018-December). IEEE, Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/NANOMED.2018.8641671
Hapuarachchi, Harini ; Premaratne, Malin. / Thermoresponsive nanohybrids for tumor imaging. Proceedings of the 12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018. IEEE, Institute of Electrical and Electronics Engineers, 2019. pp. 20-24 (IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED).
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abstract = "We demonstrate the prospect of using thermoresponsive polymer capped gold nanosphere-cadmium telluride quantum dot (QD) nanohybrids for minimally invasive detection of cancerous tissue and for feedback control of tumor temperature in localized hyperthermia therapy conducted using gold nanorods, to minimize damage to the surrounding healthy tissue. Here, we use a generalized nonlocal optical response method based cavity quantum electrodynamical formalism and show that the enhancement of the Rayleigh scattering intensity of the nanohybrid over that of the isolated gold nanosphere follows an exponential scaling with varying nanohybrid centre separation distance, in the close vicinity of the QD resonance frequency, which makes them ideal candidates for a multitude of distance based sensing applications.",
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Hapuarachchi, H & Premaratne, M 2019, Thermoresponsive nanohybrids for tumor imaging. in Proceedings of the 12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018., 8641671, IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED, vol. 2018-December, IEEE, Institute of Electrical and Electronics Engineers, pp. 20-24, IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED) 2018, Waikiki Beach, United States, 2/12/18. https://doi.org/10.1109/NANOMED.2018.8641671

Thermoresponsive nanohybrids for tumor imaging. / Hapuarachchi, Harini; Premaratne, Malin.

Proceedings of the 12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018. IEEE, Institute of Electrical and Electronics Engineers, 2019. p. 20-24 8641671 (IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED; Vol. 2018-December).

Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

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AB - We demonstrate the prospect of using thermoresponsive polymer capped gold nanosphere-cadmium telluride quantum dot (QD) nanohybrids for minimally invasive detection of cancerous tissue and for feedback control of tumor temperature in localized hyperthermia therapy conducted using gold nanorods, to minimize damage to the surrounding healthy tissue. Here, we use a generalized nonlocal optical response method based cavity quantum electrodynamical formalism and show that the enhancement of the Rayleigh scattering intensity of the nanohybrid over that of the isolated gold nanosphere follows an exponential scaling with varying nanohybrid centre separation distance, in the close vicinity of the QD resonance frequency, which makes them ideal candidates for a multitude of distance based sensing applications.

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Hapuarachchi H, Premaratne M. Thermoresponsive nanohybrids for tumor imaging. In Proceedings of the 12th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2018. IEEE, Institute of Electrical and Electronics Engineers. 2019. p. 20-24. 8641671. (IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED). https://doi.org/10.1109/NANOMED.2018.8641671