Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes

Robert Chapman; Petra J.M. Bouten; Richard Hoogenboom; Katrina A Jolliffe; Sébastien Perrier

doi:10.1039/c3cc42327a

Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes

Robert Chapman, Petra J.M. Bouten, Richard Hoogenboom, Katrina A Jolliffe, Sébastien Perrier

Research output: Contribution to journal › Article › Research › peer-review

44 Citations (Scopus)

Abstract

We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate.

Original language	English
Pages (from-to)	6522-6524
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	58
DOIs	https://doi.org/10.1039/c3cc42327a
Publication status	Published - 25 Jul 2013
Externally published	Yes

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title = "Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes",

abstract = "We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate. ",

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AU - Chapman, Robert

AU - Bouten, Petra J.M.

AU - Hoogenboom, Richard

AU - Jolliffe, Katrina A

AU - Perrier, Sébastien

PY - 2013/7/25

Y1 - 2013/7/25

N2 - We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate.

AB - We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate.

UR - https://www.scopus.com/pages/publications/84879770287

U2 - 10.1039/c3cc42327a

DO - 10.1039/c3cc42327a

M3 - Article

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VL - 49

SP - 6522

EP - 6524

JO - Chemical Communications

JF - Chemical Communications

IS - 58

ER -

Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes

Abstract

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