Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes

Robert Chapman, Petra J.M. Bouten, Richard Hoogenboom, Katrina A Jolliffe, Sébastien Perrier

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36 Citations (Scopus)


We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate. 

Original languageEnglish
Pages (from-to)6522-6524
Number of pages3
JournalChemical Communications
Issue number58
Publication statusPublished - 25 Jul 2013
Externally publishedYes

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