Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes

Robert Chapman; Petra J.M. Bouten; Richard Hoogenboom; Katrina A Jolliffe; Sébastien Perrier

doi:10.1039/c3cc42327a

Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes

Robert Chapman, Petra J.M. Bouten, Richard Hoogenboom, Katrina A Jolliffe, Sébastien Perrier

Research output: Contribution to journal › Article › Research › peer-review

31 Citations (Scopus)

Abstract

We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate.

Original language	English
Pages (from-to)	6522-6524
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	58
DOIs	https://doi.org/10.1039/c3cc42327a
Publication status	Published - 25 Jul 2013
Externally published	Yes

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10.1039/c3cc42327a

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Cite this

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title = "Thermoresponsive cyclic peptide-poly(2-ethyl-2-oxazoline) conjugate nanotubes",

abstract = "We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate. ",

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AU - Perrier, Sébastien

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AB - We describe the synthesis of self-assembling cyclic octapeptides of alternating d- and l-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate.

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