The zebrafish as a model system for human disease.

Alister C. Ward; Graham J. Lieschke

The zebrafish as a model system for human disease.

Alister C. Ward
, Graham J. Lieschke

Research output: Contribution to journal › Review Article › Research › peer-review

Abstract

The zebrafish (Danio rerio) has been widely utilised for the study of developmental biology, which has lead to the evolution of sophisticated cellular and molecular approaches. More recently, the rapid progress of various zebrafish genomic infrastructure initiatives is facilitating the development of zebrafish models of human disease. This review aims to describe several representative examples of how the zebrafish can be successfully used to identify novel genes and assign gene function, providing invaluable clues to human pathophysiology.

Original language	English
Journal	Frontiers in Bioscience
Volume	7
Publication status	Published - 2002
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

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title = "The zebrafish as a model system for human disease.",

abstract = "The zebrafish (Danio rerio) has been widely utilised for the study of developmental biology, which has lead to the evolution of sophisticated cellular and molecular approaches. More recently, the rapid progress of various zebrafish genomic infrastructure initiatives is facilitating the development of zebrafish models of human disease. This review aims to describe several representative examples of how the zebrafish can be successfully used to identify novel genes and assign gene function, providing invaluable clues to human pathophysiology.",

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AU - Ward, Alister C.

AU - Lieschke, Graham J.

PY - 2002

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AB - The zebrafish (Danio rerio) has been widely utilised for the study of developmental biology, which has lead to the evolution of sophisticated cellular and molecular approaches. More recently, the rapid progress of various zebrafish genomic infrastructure initiatives is facilitating the development of zebrafish models of human disease. This review aims to describe several representative examples of how the zebrafish can be successfully used to identify novel genes and assign gene function, providing invaluable clues to human pathophysiology.

UR - https://www.scopus.com/pages/publications/0036550238

M3 - Review Article

C2 - 11897571

AN - SCOPUS:0036550238

SN - 1093-9946

VL - 7

JO - Frontiers in Bioscience

JF - Frontiers in Bioscience

ER -

The zebrafish as a model system for human disease.

Abstract

UN SDGs

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