The Virtual Child

Richard J. Gilbertson; Sam Behjati; Anna Lisa Böttcher; Marianne E. Bronner; Matthew Burridge; Henrick Clausing; Harry Clifford; Tracey Danaher; Laura K. Donovan; Jarno Drost; Alexander M.M. Eggermont; Chris Emerson; Mona G. Flores; Petra Hamerlik; Nada Jabado; Andrew Jones; Henrick Kaessmann; Claudia L. Kleinman; Marcel Kool; Lena M. Kutscher; Gavin Lindberg; Emily Linnane; John C. Marioni; John M. Maris; Michelle Monje; Alexandra Macaskill; Steven Niederer; Paul A. Northcott; Elizabeth Peeters; Willemijn Plieger Van Solkema; Liane Preußner; Anne C. Rios; Karsten Rippe; Peter Sandford; Nikolaos G. Sgourakis; Adam Shlien; Pete Smith; Karin Straathof; Patrick J. Sullivan; Mario L. Suvà; Michael D. Taylor; Emma Thompson; Roser Vento-Tormo; Brandon J. Wainwright; Robert J. Wechsler-Reya; Frank Westermann; Shannon Winslade; Bissan Al-Lazikani; Stefan M. Pfister

doi:10.1158/2159-8290.CD-23-1500

The Virtual Child

Richard J. Gilbertson
, Sam Behjati
, Anna Lisa Böttcher
, Marianne E. Bronner
, Matthew Burridge
, Henrick Clausing
, Harry Clifford
, Tracey Danaher
, Laura K. Donovan
, Jarno Drost
, Alexander M.M. Eggermont
, Chris Emerson
, Mona G. Flores
, Petra Hamerlik
, Nada Jabado
, Andrew Jones
, Henrick Kaessmann
, Claudia L. Kleinman
, Marcel Kool
, Lena M. Kutscher

Gavin Lindberg, Emily Linnane, John C. Marioni, John M. Maris, Michelle Monje, Alexandra Macaskill, Steven Niederer, Paul A. Northcott, Elizabeth Peeters, Willemijn Plieger Van Solkema, Liane Preußner, Anne C. Rios, Karsten Rippe, Peter Sandford, Nikolaos G. Sgourakis, Adam Shlien, Pete Smith, Karin Straathof, Patrick J. Sullivan, Mario L. Suvà, Michael D. Taylor, Emma Thompson, Roser Vento-Tormo, Brandon J. Wainwright, Robert J. Wechsler-Reya, Frank Westermann, Shannon Winslade, Bissan Al-Lazikani, Stefan M. Pfister

Research output: Contribution to journal › Article › Other › peer-review

8 Citations (Scopus)

Abstract

We are building the world’s first Virtual Child–a computer model of normal and cancerous human development at the level of each individual cell. The Virtual Child will “develop cancer” that we will subject to unlimited virtual clinical trials that pinpoint, predict, and prioritize potential new treatments, bringing forward the day when no child dies of cancer, giving each one the opportunity to lead a full and healthy life.

Original language	English
Pages (from-to)	663-668
Number of pages	6
Journal	Cancer Discovery
Volume	14
Issue number	4
DOIs	https://doi.org/10.1158/2159-8290.CD-23-1500
Publication status	Published - 1 Apr 2024
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1158/2159-8290.CD-23-1500

Cite this

Gilbertson, R. J., Behjati, S., Böttcher, A. L., Bronner, M. E., Burridge, M., Clausing, H., Clifford, H., Danaher, T., Donovan, L. K., Drost, J., Eggermont, A. M. M., Emerson, C., Flores, M. G., Hamerlik, P., Jabado, N., Jones, A., Kaessmann, H., Kleinman, C. L., Kool, M., ... Pfister, S. M. (2024). The Virtual Child. Cancer Discovery, 14(4), 663-668. https://doi.org/10.1158/2159-8290.CD-23-1500

@article{fa692bb5d6a34b9fafee252c0855f16f,

title = "The Virtual Child",

abstract = "We are building the world{\textquoteright}s first Virtual Child–a computer model of normal and cancerous human development at the level of each individual cell. The Virtual Child will “develop cancer” that we will subject to unlimited virtual clinical trials that pinpoint, predict, and prioritize potential new treatments, bringing forward the day when no child dies of cancer, giving each one the opportunity to lead a full and healthy life.",

author = "Gilbertson, \{Richard J.\} and Sam Behjati and B{\"o}ttcher, \{Anna Lisa\} and Bronner, \{Marianne E.\} and Matthew Burridge and Henrick Clausing and Harry Clifford and Tracey Danaher and Donovan, \{Laura K.\} and Jarno Drost and Eggermont, \{Alexander M.M.\} and Chris Emerson and Flores, \{Mona G.\} and Petra Hamerlik and Nada Jabado and Andrew Jones and Henrick Kaessmann and Kleinman, \{Claudia L.\} and Marcel Kool and Kutscher, \{Lena M.\} and Gavin Lindberg and Emily Linnane and Marioni, \{John C.\} and Maris, \{John M.\} and Michelle Monje and Alexandra Macaskill and Steven Niederer and Northcott, \{Paul A.\} and Elizabeth Peeters and Solkema, \{Willemijn Plieger Van\} and Liane Preu{\ss}ner and Rios, \{Anne C.\} and Karsten Rippe and Peter Sandford and Sgourakis, \{Nikolaos G.\} and Adam Shlien and Pete Smith and Karin Straathof and Sullivan, \{Patrick J.\} and Suv{\`a}, \{Mario L.\} and Taylor, \{Michael D.\} and Emma Thompson and Roser Vento-Tormo and Wainwright, \{Brandon J.\} and Wechsler-Reya, \{Robert J.\} and Frank Westermann and Shannon Winslade and Bissan Al-Lazikani and Pfister, \{Stefan M.\}",

note = "Publisher Copyright: {\textcopyright} 2024 American Association for Cancer Research.",

year = "2024",

month = apr,

day = "1",

doi = "10.1158/2159-8290.CD-23-1500",

language = "English",

volume = "14",

pages = "663--668",

journal = "Cancer Discovery",

issn = "2159-8274",

publisher = "American Association for Cancer Research (AACR)",

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}

Gilbertson, RJ, Behjati, S, Böttcher, AL, Bronner, ME, Burridge, M, Clausing, H, Clifford, H, Danaher, T, Donovan, LK, Drost, J, Eggermont, AMM, Emerson, C, Flores, MG, Hamerlik, P, Jabado, N, Jones, A, Kaessmann, H, Kleinman, CL, Kool, M, Kutscher, LM, Lindberg, G, Linnane, E, Marioni, JC, Maris, JM, Monje, M, Macaskill, A, Niederer, S, Northcott, PA, Peeters, E, Solkema, WPV, Preußner, L, Rios, AC, Rippe, K, Sandford, P, Sgourakis, NG, Shlien, A, Smith, P, Straathof, K, Sullivan, PJ, Suvà, ML, Taylor, MD, Thompson, E, Vento-Tormo, R, Wainwright, BJ, Wechsler-Reya, RJ, Westermann, F, Winslade, S, Al-Lazikani, B & Pfister, SM 2024, 'The Virtual Child', Cancer Discovery, vol. 14, no. 4, pp. 663-668. https://doi.org/10.1158/2159-8290.CD-23-1500

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AU - Gilbertson, Richard J.

AU - Behjati, Sam

AU - Böttcher, Anna Lisa

AU - Bronner, Marianne E.

AU - Burridge, Matthew

AU - Clausing, Henrick

AU - Clifford, Harry

AU - Danaher, Tracey

AU - Donovan, Laura K.

AU - Drost, Jarno

AU - Eggermont, Alexander M.M.

AU - Emerson, Chris

AU - Flores, Mona G.

AU - Hamerlik, Petra

AU - Jabado, Nada

AU - Jones, Andrew

AU - Kaessmann, Henrick

AU - Kleinman, Claudia L.

AU - Kool, Marcel

AU - Kutscher, Lena M.

AU - Lindberg, Gavin

AU - Linnane, Emily

AU - Marioni, John C.

AU - Maris, John M.

AU - Monje, Michelle

AU - Macaskill, Alexandra

AU - Niederer, Steven

AU - Northcott, Paul A.

AU - Peeters, Elizabeth

AU - Solkema, Willemijn Plieger Van

AU - Preußner, Liane

AU - Rios, Anne C.

AU - Rippe, Karsten

AU - Sandford, Peter

AU - Sgourakis, Nikolaos G.

AU - Shlien, Adam

AU - Smith, Pete

AU - Straathof, Karin

AU - Sullivan, Patrick J.

AU - Suvà, Mario L.

AU - Taylor, Michael D.

AU - Thompson, Emma

AU - Vento-Tormo, Roser

AU - Wainwright, Brandon J.

AU - Wechsler-Reya, Robert J.

AU - Westermann, Frank

AU - Winslade, Shannon

AU - Al-Lazikani, Bissan

AU - Pfister, Stefan M.

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AB - We are building the world’s first Virtual Child–a computer model of normal and cancerous human development at the level of each individual cell. The Virtual Child will “develop cancer” that we will subject to unlimited virtual clinical trials that pinpoint, predict, and prioritize potential new treatments, bringing forward the day when no child dies of cancer, giving each one the opportunity to lead a full and healthy life.

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DO - 10.1158/2159-8290.CD-23-1500

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AN - SCOPUS:85190085783

SN - 2159-8274

VL - 14

SP - 663

EP - 668

JO - Cancer Discovery

JF - Cancer Discovery

IS - 4

ER -

The Virtual Child

Abstract

UN SDGs

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