The vasoneuronal effects of AT1 receptor blockade in a rat model of retinopathy of prematurity

Kate Hatzopoulos, Kirstan A Vessey, Jennifer Wilkinson-Berka, Erica Lucy Fletcher

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Abstract

Retinal angiogenesis, neural dysfunction, and microglial activation occur in both humans with retinopathy of prematurity and in animal models of the disease. The aim of this study was to assess whether blockade of the renin-angiotensin system ameliorated these effects in rats with oxygen induced retinopathy (OIR).
Original languageEnglish
Pages (from-to)3957 - 3970
Number of pages14
JournalInvestigative Ophthalmology and Visual Science
Volume55
Issue number6
DOIs
Publication statusPublished - 2014

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