Abstract
A series of 30 tripeptides were synthesized and tested as novel 5-HT4 receptor ligands. Receptor binding assays showed that a subset of compounds had reasonable potency relative to the agonists serotonin and 5-methoxytryptamine. Structure-activity analyses and molecular docking have highlighted avenues for further synthetic work.
| Original language | English |
|---|---|
| Pages (from-to) | 805 - 809 |
| Number of pages | 5 |
| Journal | Protein and Peptide Letters |
| Volume | 16 |
| Issue number | 7 |
| Publication status | Published - 2009 |