Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 77 - 88 |
| Number of pages | 12 |
| Journal | International Journal of STD and AIDS |
| Volume | 25 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2014 |
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The two-edged sword: vasculitis associated with HIV and hepatitis C coinfection. / Ojaimi, Samar; Lin, Ming-Wei; Singh, Kasha; Woolley, Ian John.
In: International Journal of STD and AIDS, Vol. 25, No. 2, 2014, p. 77 - 88.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - The two-edged sword: vasculitis associated with HIV and hepatitis C coinfection
AU - Ojaimi, Samar
AU - Lin, Ming-Wei
AU - Singh, Kasha
AU - Woolley, Ian John
PY - 2014
Y1 - 2014
N2 - Vasculitis has long been associated with chronic viral infections, thus the twin perils of the infection and the immune response against it that bedevils the specialties of infection and immunity. After HIV was identified, it too became associated with vasculitic syndromes. Later, hepatitis C virus was also isolated, identified and described with its own spectrum of vasculitic diseases, including hepatitis C virus-associated cryoglobulinaemia. With the increasing prevalence of HIV and hepatitis C virus coinfection, there has come an increasing recognition of the range of vasculitides that can occur in this population leading to significant morbidity, diagnostic and treatment challenges. In this review, we examine the epidemiology, pathogenesis and general principles of treatment of these systemic diseases in HIV/hepatitis C virus coinfected individuals.
AB - Vasculitis has long been associated with chronic viral infections, thus the twin perils of the infection and the immune response against it that bedevils the specialties of infection and immunity. After HIV was identified, it too became associated with vasculitic syndromes. Later, hepatitis C virus was also isolated, identified and described with its own spectrum of vasculitic diseases, including hepatitis C virus-associated cryoglobulinaemia. With the increasing prevalence of HIV and hepatitis C virus coinfection, there has come an increasing recognition of the range of vasculitides that can occur in this population leading to significant morbidity, diagnostic and treatment challenges. In this review, we examine the epidemiology, pathogenesis and general principles of treatment of these systemic diseases in HIV/hepatitis C virus coinfected individuals.
UR - http://www.ncbi.nlm.nih.gov/pubmed/23970639
U2 - 10.1177/0956462413495671
DO - 10.1177/0956462413495671
M3 - Article
VL - 25
SP - 77
EP - 88
JO - International Journal of STD and AIDS
JF - International Journal of STD and AIDS
SN - 0956-4624
IS - 2
ER -