The transcription factor Pokemon: A new key player in cancer pathogenesis

Takahiro Maeda; Robin M. Hobbs; Pier Paolo Pandolfi

doi:10.1158/0008-5472.CAN-05-1055

The transcription factor Pokemon: A new key player in cancer pathogenesis

Takahiro Maeda
, Robin M. Hobbs
, Pier Paolo Pandolfi

Research output: Contribution to journal › Review Article › Research › peer-review

95 Citations (Scopus)

Abstract

Learning how critical cell regulatory pathways are controlled may lead to new opportunities for cancer treatment. We recently identified the transcription factor Pokemon as a central regulator of the important tumor suppressor ARF. Pokemon is overexpressed in multiple human cancers and cells lacking Pokemon are refractory to oncogenic transformation. These findings suggest that Pokemon may offer an effective new target for cancer therapeutics.

Original language	English
Pages (from-to)	8575-8578
Number of pages	4
Journal	Cancer Research
Volume	65
Issue number	19
DOIs	https://doi.org/10.1158/0008-5472.CAN-05-1055
Publication status	Published - 1 Oct 2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1158/0008-5472.CAN-05-1055

Cite this

@article{bd6c2a9744a04552a82549a3899b6ad9,

title = "The transcription factor Pokemon: A new key player in cancer pathogenesis",

abstract = "Learning how critical cell regulatory pathways are controlled may lead to new opportunities for cancer treatment. We recently identified the transcription factor Pokemon as a central regulator of the important tumor suppressor ARF. Pokemon is overexpressed in multiple human cancers and cells lacking Pokemon are refractory to oncogenic transformation. These findings suggest that Pokemon may offer an effective new target for cancer therapeutics.",

author = "Takahiro Maeda and Hobbs, \{Robin M.\} and Pandolfi, \{Pier Paolo\}",

year = "2005",

month = oct,

day = "1",

doi = "10.1158/0008-5472.CAN-05-1055",

language = "English",

volume = "65",

pages = "8575--8578",

journal = "Cancer Research",

issn = "0008-5472",

publisher = "American Association for Cancer Research (AACR)",

number = "19",

}

TY - JOUR

T1 - The transcription factor Pokemon

T2 - A new key player in cancer pathogenesis

AU - Maeda, Takahiro

AU - Hobbs, Robin M.

AU - Pandolfi, Pier Paolo

PY - 2005/10/1

Y1 - 2005/10/1

N2 - Learning how critical cell regulatory pathways are controlled may lead to new opportunities for cancer treatment. We recently identified the transcription factor Pokemon as a central regulator of the important tumor suppressor ARF. Pokemon is overexpressed in multiple human cancers and cells lacking Pokemon are refractory to oncogenic transformation. These findings suggest that Pokemon may offer an effective new target for cancer therapeutics.

AB - Learning how critical cell regulatory pathways are controlled may lead to new opportunities for cancer treatment. We recently identified the transcription factor Pokemon as a central regulator of the important tumor suppressor ARF. Pokemon is overexpressed in multiple human cancers and cells lacking Pokemon are refractory to oncogenic transformation. These findings suggest that Pokemon may offer an effective new target for cancer therapeutics.

UR - https://www.scopus.com/pages/publications/25444476684

U2 - 10.1158/0008-5472.CAN-05-1055

DO - 10.1158/0008-5472.CAN-05-1055

M3 - Review Article

C2 - 16204018

AN - SCOPUS:25444476684

SN - 0008-5472

VL - 65

SP - 8575

EP - 8578

JO - Cancer Research

JF - Cancer Research

IS - 19

ER -

The transcription factor Pokemon: A new key player in cancer pathogenesis

Abstract

UN SDGs

Access to Document

Other files and links

Cite this