Abstract
The targeting of newly-made polypeptides to specific membranes, and the subsequent ability of a membrane to allow only certain polypeptides into its compartment, are essential to maintain the ultrastructure of Eukaryotic cells. Distinct oligomeric protein complexes in each cellular membrane catalyse these translocation processes. A recent report [Hill K et al. Nature 1998;395:516-521 (Ref. 1)] of the reconstitution of the translocation channel from the mitochondrial outer membrane, after producing the major structural component of the channel by recombinant means, promises a system to dissect in molecular detail the exact working of one of these protein translocation machines.
Original language | English |
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Pages (from-to) | 1-4 |
Number of pages | 4 |
Journal | BioEssays |
Volume | 21 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 1999 |
Externally published | Yes |