The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized EWES

Iain J. Clarke; James T. Cummins

doi:10.1210/endo-111-5-1737

The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized EWES

Iain J. Clarke, James T. Cummins

Research output: Contribution to journal › Article › Research › peer-review

537 Citations (Scopus)

Abstract

Hypothalamo-hypophyseal portal blood has been collected from conscious OVX ewes by a procedure that permits maintenance of pituitary function. GnRH was measured in portal plasma and LH was measured in peripheral (jugular) plasma. The data demonstrate exact synchrony of GnRH and LH secretion. We conclude that each pulsatile LH secretory episode results from a pulsatile discharge of GnRH from the hypothalamus via the portal network.

Original language	English
Pages (from-to)	1737-1739
Number of pages	3
Journal	Endocrinology
Volume	111
Issue number	5
DOIs	https://doi.org/10.1210/endo-111-5-1737
Publication status	Published - 1 Jan 1982
Externally published	Yes

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title = "The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized EWES",

abstract = "Hypothalamo-hypophyseal portal blood has been collected from conscious OVX ewes by a procedure that permits maintenance of pituitary function. GnRH was measured in portal plasma and LH was measured in peripheral (jugular) plasma. The data demonstrate exact synchrony of GnRH and LH secretion. We conclude that each pulsatile LH secretory episode results from a pulsatile discharge of GnRH from the hypothalamus via the portal network.",

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AB - Hypothalamo-hypophyseal portal blood has been collected from conscious OVX ewes by a procedure that permits maintenance of pituitary function. GnRH was measured in portal plasma and LH was measured in peripheral (jugular) plasma. The data demonstrate exact synchrony of GnRH and LH secretion. We conclude that each pulsatile LH secretory episode results from a pulsatile discharge of GnRH from the hypothalamus via the portal network.

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The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized EWES

Abstract

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