The stereochemistry of organometallic compounds. XXXVI. Rhodium-catalysed reactions of unsaturated amines with hydrogen and carbon monoxide. A new synthesis of 2-piperidinones

Despina Anastasiou; W. Roy Jackson

doi:10.1016/0022-328X(91)80065-R

The stereochemistry of organometallic compounds. XXXVI. Rhodium-catalysed reactions of unsaturated amines with hydrogen and carbon monoxide. A new synthesis of 2-piperidinones

Despina Anastasiou, W. Roy Jackson

School of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

16 Citations (Scopus)

Abstract

Rhodium-catalysed reactions of 5-aminopent-1-enes with carbon monoxide and hydrogen give 2-piperidinone derivatives in high yields under mild conditions. Reaction of allylamine under similar conditions gave exclusively 2-pyrrolidone in high yield and reactions of 4-aminobut-1-enes gave mixtures of 2-piperidinones and 2-pyrrolidinones. The role of the hydrogen in these reactions is discussed.

Original language	English
Pages (from-to)	399-410
Number of pages	12
Journal	Journal of Organometallic Chemistry
Volume	413
Issue number	1-3
DOIs	https://doi.org/10.1016/0022-328X(91)80065-R
Publication status	Published - 7 Aug 1991

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abstract = "Rhodium-catalysed reactions of 5-aminopent-1-enes with carbon monoxide and hydrogen give 2-piperidinone derivatives in high yields under mild conditions. Reaction of allylamine under similar conditions gave exclusively 2-pyrrolidone in high yield and reactions of 4-aminobut-1-enes gave mixtures of 2-piperidinones and 2-pyrrolidinones. The role of the hydrogen in these reactions is discussed.",

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The stereochemistry of organometallic compounds. XXXVI. Rhodium-catalysed reactions of unsaturated amines with hydrogen and carbon monoxide. A new synthesis of 2-piperidinones. / Anastasiou, Despina; Jackson, W. Roy.
In: Journal of Organometallic Chemistry, Vol. 413, No. 1-3, 07.08.1991, p. 399-410.

Research output: Contribution to journal › Article › Research › peer-review

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AB - Rhodium-catalysed reactions of 5-aminopent-1-enes with carbon monoxide and hydrogen give 2-piperidinone derivatives in high yields under mild conditions. Reaction of allylamine under similar conditions gave exclusively 2-pyrrolidone in high yield and reactions of 4-aminobut-1-enes gave mixtures of 2-piperidinones and 2-pyrrolidinones. The role of the hydrogen in these reactions is discussed.

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The stereochemistry of organometallic compounds. XXXVI. Rhodium-catalysed reactions of unsaturated amines with hydrogen and carbon monoxide. A new synthesis of 2-piperidinones

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