The stereochemistry of organometallic compounds. XXXVI. Regio- and stereo-chemical control in the nickel-catalysed hydrocyanation of silylalkynes

Neil J. Fitzmaurice, W. Roy Jackson, Patrick Perlmutter

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

Abstract

The regioselectivity of hydrocyanation of silylalkynes can be controlled by varying the size of the groups attached to silicon leading, for example, to efficient preparations of E-3-trialkylsilyl-2-alkyl-2-alkenenitriles. High yields of the silylalkene nitriles can be obtained by using either acetone cyanohydrin or hydrogen cyanide as reagents.

Original languageEnglish
Pages (from-to)375-381
Number of pages7
JournalJournal of Organometallic Chemistry
Volume285
Issue number1-3
DOIs
Publication statusPublished - 16 Apr 1985

Cite this