The stereochemistry of organometallic compounds. XXXVI. Regio- and stereo-chemical control in the nickel-catalysed hydrocyanation of silylalkynes

Neil J. Fitzmaurice, W. Roy Jackson, Patrick Perlmutter

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The regioselectivity of hydrocyanation of silylalkynes can be controlled by varying the size of the groups attached to silicon leading, for example, to efficient preparations of E-3-trialkylsilyl-2-alkyl-2-alkenenitriles. High yields of the silylalkene nitriles can be obtained by using either acetone cyanohydrin or hydrogen cyanide as reagents.

Original languageEnglish
Pages (from-to)375-381
Number of pages7
JournalJournal of Organometallic Chemistry
Issue number1-3
Publication statusPublished - 16 Apr 1985

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