The stereochemistry of organometallic compounds. XXX hydrocyanation of alkynol ethers: A new stereospecific route to α-alkylidene γ-lactones

W. Roy Jackson, Patrick Perlmutter, Andrew J. Smallridge

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Abstract

The regioselectivity of hydrocyanation of a range of protected α- and β-hydroxyalkynes has been investigated and shown to be highly susceptible to steric effects. Some of the products from hydrocyanation of protected β-hydroxyalkynes have been converted into α-alkylidene γ-lactones.

Original languageEnglish
Pages (from-to)251-261
Number of pages11
JournalAustralian Journal of Chemistry
Volume41
Issue number2
DOIs
Publication statusPublished - 1 Jan 1988

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