The start-ups taking nanoneedles into the clinic

Roey Elnathan, Andy Tay, Nicolas H. Voelcker, Ciro Chiappini

Research output: Contribution to journalComment / DebateOtherpeer-review

3 Citations (Scopus)


Nanotechnology has matured to the point where it provides exquisite solutions to key challenges across medicine and biology, as seen in the success of delivery nanovectors for COVID-19vaccines1. Among these nanotechnologies, nanoneedles — vertical arrays of high aspect-ratio nanomaterials — have emerged as a simple, controllable and powerful tool to efficiently access cells with minimalperturbation2. Nanoneedles are rapidly emerging as competitive solutions forsensing3, and offer a path to transforming gene and cell therapies4,5. Realizing the transformative potential of nanoneedles is a work in progress. In this Comment, we discuss the burgeoning advances and strong commercial activities of nanoneedle technology through the eyes of leading researchers, entrepreneurs and venture capitalists — all of them major players in the evolution of a viable nanoneedle technology for sensing and clinical use.
Original languageEnglish
Pages (from-to)807-811
Number of pages5
JournalNature Nanotechnology
Issue number8
Publication statusPublished - Aug 2022

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