The role of the oral-gut microbiome axis in connecting periodontitis with gastrointestinal and systemic diseases

Jodi Woan-Fei Law; Mei Zhong; Vengadesh Letchumanan; Loh Teng-Hern Tan; Lijing Wen; Learn-Han Lee

doi:10.1136/gutjnl-2024-IDDF.139

The role of the oral-gut microbiome axis in connecting periodontitis with gastrointestinal and systemic diseases

Jodi Woan-Fei Law, Mei Zhong, Vengadesh Letchumanan, Loh Teng-Hern Tan, Lijing Wen, Learn-Han Lee

Malaysia Jeffrey Cheah Sch of Med & HS

Research output: Contribution to journal › Meeting Abstract › peer-review

Abstract

Periodontitis is characterized by oral bacterial dysbiosis causing persistent inflammation in dental supporting tissue, leading to tissue breakdown and bone loss. The colonization of periodontal pathogens in the gastrointestinal tract has contributed to inflammatory gastrointestinal disease pathogenesis. This research aims to investigate changes in the gut microbiome caused by periodontitis and their association with the development of gastrointestinal and systemic diseases.

Original language	English
Article number	IDDF2024-ABS-0372
Pages (from-to)	A214-A215
Number of pages	2
Journal	Gut
Volume	73
Issue number	S2
DOIs	https://doi.org/10.1136/gutjnl-2024-IDDF.139
Publication status	Published - Aug 2024
Event	International Digestive Disease Forum 2024 - , Hong Kong Duration: 10 Aug 2024 → 11 Aug 2024 https://gut.bmj.com/content/73/Suppl_2 (published abstracts)

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10.1136/gutjnl-2024-IDDF.139

Cite this

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title = "The role of the oral-gut microbiome axis in connecting periodontitis with gastrointestinal and systemic diseases",

abstract = "Periodontitis is characterized by oral bacterial dysbiosis causing persistent inflammation in dental supporting tissue, leading to tissue breakdown and bone loss. The colonization of periodontal pathogens in the gastrointestinal tract has contributed to inflammatory gastrointestinal disease pathogenesis. This research aims to investigate changes in the gut microbiome caused by periodontitis and their association with the development of gastrointestinal and systemic diseases.",

author = "Law, {Jodi Woan-Fei} and Mei Zhong and Vengadesh Letchumanan and Tan, {Loh Teng-Hern} and Lijing Wen and Learn-Han Lee",

year = "2024",

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doi = "10.1136/gutjnl-2024-IDDF.139",

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journal = "Gut",

issn = "0017-5749",

publisher = "BMJ",

number = "S2",

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T1 - The role of the oral-gut microbiome axis in connecting periodontitis with gastrointestinal and systemic diseases

AU - Law, Jodi Woan-Fei

AU - Zhong, Mei

AU - Letchumanan, Vengadesh

AU - Tan, Loh Teng-Hern

AU - Wen, Lijing

AU - Lee, Learn-Han

PY - 2024/8

Y1 - 2024/8

N2 - Periodontitis is characterized by oral bacterial dysbiosis causing persistent inflammation in dental supporting tissue, leading to tissue breakdown and bone loss. The colonization of periodontal pathogens in the gastrointestinal tract has contributed to inflammatory gastrointestinal disease pathogenesis. This research aims to investigate changes in the gut microbiome caused by periodontitis and their association with the development of gastrointestinal and systemic diseases.

AB - Periodontitis is characterized by oral bacterial dysbiosis causing persistent inflammation in dental supporting tissue, leading to tissue breakdown and bone loss. The colonization of periodontal pathogens in the gastrointestinal tract has contributed to inflammatory gastrointestinal disease pathogenesis. This research aims to investigate changes in the gut microbiome caused by periodontitis and their association with the development of gastrointestinal and systemic diseases.

U2 - 10.1136/gutjnl-2024-IDDF.139

DO - 10.1136/gutjnl-2024-IDDF.139

M3 - Meeting Abstract

SN - 0017-5749

VL - 73

SP - A214-A215

JO - Gut

JF - Gut

IS - S2

M1 - IDDF2024-ABS-0372

T2 - International Digestive Disease Forum 2024

Y2 - 10 August 2024 through 11 August 2024

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