Congenital hypothyroidism (CH), as indicated by an elevation of capillary thyroid-stimulating hormone (TSH) at newborn screening, is a preventable cause of mental retardation with varying aetiology; it can be transient or permanent. Radionuclide assessment is currently the gold standard for imaging CH. This study aimed to (i) review the different scintigraphic patterns and correlate them with TSH levels/patient outcomes, (ii) assess the role of sonography in neonates with apparent agenesis as indicated by scintigraphy and (iii) devleop a diagnostic investigative algorithm.
de Silva, A., Jong, I., McLean, G., Bergman, P. B., Rodda, C. P., Brown, J., & Nandurkar, D. (2014). The role of scintigraphy and ultrasound in the imaging of neonatal hypothyroidism: 5-year retrospective review of single-centre experience. Journal of Medical Imaging and Radiation Oncology, 58(4), 422 - 430. https://doi.org/10.1111/1754-9485.12166