TY - JOUR
T1 - The role of scintigraphy and ultrasound in the imaging of neonatal hypothyroidism: 5-year retrospective review of single-centre experience
AU - de Silva, Ami
AU - Jong, Ian
AU - McLean, Glenda
AU - Bergman, Philip Bruce
AU - Rodda, Christine P
AU - Brown, Justin
AU - Nandurkar, Dee
PY - 2014
Y1 - 2014
N2 - Congenital hypothyroidism (CH), as indicated by an elevation of capillary thyroid-stimulating hormone (TSH) at newborn screening, is a preventable cause of mental retardation with varying aetiology; it can be transient or permanent. Radionuclide assessment is currently the gold standard for imaging CH. This study aimed to (i) review the different scintigraphic patterns and correlate them with TSH levels/patient outcomes, (ii) assess the role of sonography in neonates with apparent agenesis as indicated by scintigraphy and (iii) devleop a diagnostic investigative algorithm.
AB - Congenital hypothyroidism (CH), as indicated by an elevation of capillary thyroid-stimulating hormone (TSH) at newborn screening, is a preventable cause of mental retardation with varying aetiology; it can be transient or permanent. Radionuclide assessment is currently the gold standard for imaging CH. This study aimed to (i) review the different scintigraphic patterns and correlate them with TSH levels/patient outcomes, (ii) assess the role of sonography in neonates with apparent agenesis as indicated by scintigraphy and (iii) devleop a diagnostic investigative algorithm.
UR - http://onlinelibrary.wiley.com/doi/10.1111/1754-9485.12166/pdf
U2 - 10.1111/1754-9485.12166
DO - 10.1111/1754-9485.12166
M3 - Article
SN - 1754-9477
VL - 58
SP - 422
EP - 430
JO - Journal of Medical Imaging and Radiation Oncology
JF - Journal of Medical Imaging and Radiation Oncology
IS - 4
ER -