The role of scintigraphy and ultrasound in the imaging of neonatal hypothyroidism: 5-year retrospective review of single-centre experience

Ami de Silva, Ian Jong, Glenda McLean, Philip Bruce Bergman, Christine P Rodda, Justin Brown, Dee Nandurkar

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Congenital hypothyroidism (CH), as indicated by an elevation of capillary thyroid-stimulating hormone (TSH) at newborn screening, is a preventable cause of mental retardation with varying aetiology; it can be transient or permanent. Radionuclide assessment is currently the gold standard for imaging CH. This study aimed to (i) review the different scintigraphic patterns and correlate them with TSH levels/patient outcomes, (ii) assess the role of sonography in neonates with apparent agenesis as indicated by scintigraphy and (iii) devleop a diagnostic investigative algorithm.
Original languageEnglish
Pages (from-to)422 - 430
Number of pages9
JournalJournal of Medical Imaging and Radiation Oncology
Volume58
Issue number4
DOIs
Publication statusPublished - 2014

Cite this

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title = "The role of scintigraphy and ultrasound in the imaging of neonatal hypothyroidism: 5-year retrospective review of single-centre experience",
abstract = "Congenital hypothyroidism (CH), as indicated by an elevation of capillary thyroid-stimulating hormone (TSH) at newborn screening, is a preventable cause of mental retardation with varying aetiology; it can be transient or permanent. Radionuclide assessment is currently the gold standard for imaging CH. This study aimed to (i) review the different scintigraphic patterns and correlate them with TSH levels/patient outcomes, (ii) assess the role of sonography in neonates with apparent agenesis as indicated by scintigraphy and (iii) devleop a diagnostic investigative algorithm.",
author = "{de Silva}, Ami and Ian Jong and Glenda McLean and Bergman, {Philip Bruce} and Rodda, {Christine P} and Justin Brown and Dee Nandurkar",
year = "2014",
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language = "English",
volume = "58",
pages = "422 -- 430",
journal = "Journal of Medical Imaging and Radiation Oncology",
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The role of scintigraphy and ultrasound in the imaging of neonatal hypothyroidism: 5-year retrospective review of single-centre experience. / de Silva, Ami; Jong, Ian; McLean, Glenda; Bergman, Philip Bruce; Rodda, Christine P; Brown, Justin; Nandurkar, Dee.

In: Journal of Medical Imaging and Radiation Oncology, Vol. 58, No. 4, 2014, p. 422 - 430.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - The role of scintigraphy and ultrasound in the imaging of neonatal hypothyroidism: 5-year retrospective review of single-centre experience

AU - de Silva, Ami

AU - Jong, Ian

AU - McLean, Glenda

AU - Bergman, Philip Bruce

AU - Rodda, Christine P

AU - Brown, Justin

AU - Nandurkar, Dee

PY - 2014

Y1 - 2014

N2 - Congenital hypothyroidism (CH), as indicated by an elevation of capillary thyroid-stimulating hormone (TSH) at newborn screening, is a preventable cause of mental retardation with varying aetiology; it can be transient or permanent. Radionuclide assessment is currently the gold standard for imaging CH. This study aimed to (i) review the different scintigraphic patterns and correlate them with TSH levels/patient outcomes, (ii) assess the role of sonography in neonates with apparent agenesis as indicated by scintigraphy and (iii) devleop a diagnostic investigative algorithm.

AB - Congenital hypothyroidism (CH), as indicated by an elevation of capillary thyroid-stimulating hormone (TSH) at newborn screening, is a preventable cause of mental retardation with varying aetiology; it can be transient or permanent. Radionuclide assessment is currently the gold standard for imaging CH. This study aimed to (i) review the different scintigraphic patterns and correlate them with TSH levels/patient outcomes, (ii) assess the role of sonography in neonates with apparent agenesis as indicated by scintigraphy and (iii) devleop a diagnostic investigative algorithm.

UR - http://onlinelibrary.wiley.com/doi/10.1111/1754-9485.12166/pdf

U2 - 10.1111/1754-9485.12166

DO - 10.1111/1754-9485.12166

M3 - Article

VL - 58

SP - 422

EP - 430

JO - Journal of Medical Imaging and Radiation Oncology

JF - Journal of Medical Imaging and Radiation Oncology

SN - 1754-9477

IS - 4

ER -