The role of omega-3 polyunsaturated fatty acids in food intake and energy homeostasis

Richard S. Weisinger, Denovan P. Begg, Lauren Stahl, Harrison S. Weisinger, Andrew J. Sinclair, Markandeya Jois

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

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Obesity, the excess accumulation of adipose tissue, is a major health problem worldwide. It is associated with more than 30 medical conditions, including type 2 diabetes and cardiovascular disease, and is a leading cause of unnecessary deaths. The control of body energy homeostasis is fundamental to mammalian life as well as to the problem of obesity. This chapter will describe the role of the omega-3 polyunsaturated fatty acids (n-3 PUFAs) in modulating some of the mechanisms that control body energy homeostasis. The chapter is divided into three major sections. The (rst section is dedicated to the dietary intake and metabolism of the n-3 PUFAs, as well as the interrelated n-6 PUFAs. The second section describes the major mechanisms responsible for the maintenance of body energy homeostasis. Then, in the third section, evidence regarding the role of n-3 PUFAs in these homeostatic mechanisms will be described, including evidence regarding the role of n-3 PUFAs in obesity and cancer cachexia.

Original languageEnglish
Title of host publicationFatty Acids in Foods and their Health Implications, Third Edition
PublisherCRC Press
Number of pages18
ISBN (Electronic)9781420006902
ISBN (Print)9780849372612
Publication statusPublished - 1 Jan 2007

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