The role of naive T-cells in HIV-1 pathogenesis: An emerging key player.

Gabriela Khoury; Reena Rajasuriar; Sharon Lewin; Paul Cameron

The role of naive T-cells in HIV-1 pathogenesis: An emerging key player.

Gabriela Khoury, Reena Rajasuriar, Sharon Lewin, Paul Cameron

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Here we review the basic homeostatic mechanisms that maintain naive CD4+ T-cells and discuss recent developments in understanding the impact of HIV infection on naive CD4+ T-cells. Finally we review therapeutic interventions in HIV-infected individuals aimed at specifically enhancing recovery of naive CD4+ T-cells.

Original language	English
Pages (from-to)	253 - 267
Number of pages	15
Journal	Clinical Immunology
Volume	141
Issue number	3
Publication status	Published - 2011

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title = "The role of naive T-cells in HIV-1 pathogenesis: An emerging key player.",

abstract = "Here we review the basic homeostatic mechanisms that maintain naive CD4+ T-cells and discuss recent developments in understanding the impact of HIV infection on naive CD4+ T-cells. Finally we review therapeutic interventions in HIV-infected individuals aimed at specifically enhancing recovery of naive CD4+ T-cells.",

author = "Gabriela Khoury and Reena Rajasuriar and Sharon Lewin and Paul Cameron",

year = "2011",

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journal = "Clinical Immunology",

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AU - Lewin, Sharon

AU - Cameron, Paul

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AB - Here we review the basic homeostatic mechanisms that maintain naive CD4+ T-cells and discuss recent developments in understanding the impact of HIV infection on naive CD4+ T-cells. Finally we review therapeutic interventions in HIV-infected individuals aimed at specifically enhancing recovery of naive CD4+ T-cells.

UR - http://www.ncbi.nlm.nih.gov/pubmed/21996455

M3 - Article

VL - 141

SP - 253

EP - 267

JO - Clinical Immunology

JF - Clinical Immunology

SN - 1521-6616

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