The role of magnetic resonance imaging in the diagnosis and management of prostate cancer

James Thompson, Nathan Lawrentschuk, Mark Frydenberg, Leslie Thompson, Phillip D Stricker

Research output: Contribution to journalArticleResearchpeer-review

100 Citations (Scopus)

Abstract

BACKGROUND: The diagnosis of prostate cancer has long been plagued by the absence of an imaging tool that reliably detects and localises significant tumours. Recent evidence suggests that multi-parametric MRI could improve the accuracy of diagnostic assessment in prostate cancer. This review serves as a background to a recent USANZ position statement. It aims to provide an overview of MRI techniques and to critically review the published literature on the clinical application of MRI in prostate cancer. TECHNICAL ASPECTS: The combination of anatomical (T2-weighted) MRI with at least two of the three functional MRI parameters - which include diffusion-weighted imaging, dynamic contrast-enhanced imaging and spectroscopy - will detect greater than 90 of significant (moderate to high risk) tumours; however MRI is less reliable at detecting tumours that are small (
Original languageEnglish
Pages (from-to)6 - 20
Number of pages15
JournalBJU International
Volume112
Issue numberSuppl 2
DOIs
Publication statusPublished - 2013

Cite this