Abstract
Sperm motility is crucial to natural fertilisation, but sperm migration behaviour at soft interfaces that represents the in vivo environment is still unexplored. Using droplet-based microfluidics, we study the effects of surface curvature and sperm-surface interactions on sperm swimming characteristics. Droplets ranging in radius from 50 µm to 120 µm are produced to study sperm motility parameters at soft interfaces. The results reveal that sperm exhibit distinct motility characteristics depending on the size of the enclosed droplets. This study brings new insights into the biophysics of sperm migration through the female reproductive tract.
| Original language | English |
|---|---|
| Title of host publication | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1538-1539 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419000 |
| Publication status | Published - 2019 |
| Event | International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Congress Center Basel, Basel, Switzerland Duration: 27 Oct 2019 → 31 Oct 2019 Conference number: 23rd https://microtas2019.org/ |
Conference
| Conference | International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 |
|---|---|
| Abbreviated title | MicroTAS 2019 |
| Country | Switzerland |
| City | Basel |
| Period | 27/10/19 → 31/10/19 |
| Other | The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019) 27 - 31 October 2019 Conference Chairs: Petra Dittrich - ETH Zürich, SWITZERLAND Andreas Hierlemann - ETH Zürich, SWITZERLAND Emmanuel Delamarche - IBM Research - Zürich, SWITZERLAND Conference Location: Congress Center Basel Basel, SWITZERLAND www.congress.ch |
| Internet address |
Keywords
- Droplet microfluidics
- Motility
- Reproduction
- Sperm