The role of interface curvature on sperm behaviour

Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

Abstract

Sperm motility is crucial to natural fertilisation, but sperm migration behaviour at soft interfaces that represents the in vivo environment is still unexplored. Using droplet-based microfluidics, we study the effects of surface curvature and sperm-surface interactions on sperm swimming characteristics. Droplets ranging in radius from 50 µm to 120 µm are produced to study sperm motility parameters at soft interfaces. The results reveal that sperm exhibit distinct motility characteristics depending on the size of the enclosed droplets. This study brings new insights into the biophysics of sperm migration through the female reproductive tract.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages1538-1539
Number of pages2
ISBN (Electronic)9781733419000
Publication statusPublished - 2019
EventInternational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Congress Center Basel, Basel, Switzerland
Duration: 27 Oct 201931 Oct 2019
Conference number: 23rd
https://microtas2019.org/

Conference

ConferenceInternational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Abbreviated titleMicroTAS 2019
CountrySwitzerland
CityBasel
Period27/10/1931/10/19
OtherThe 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019)
27 - 31 October 2019
Conference Chairs:
Petra Dittrich - ETH Zürich, SWITZERLAND
Andreas Hierlemann - ETH Zürich, SWITZERLAND
Emmanuel Delamarche - IBM Research - Zürich, SWITZERLAND
Conference Location:
Congress Center Basel
Basel, SWITZERLAND
www.congress.ch
Internet address

Keywords

  • Droplet microfluidics
  • Motility
  • Reproduction
  • Sperm

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