TY - JOUR
T1 - The role of anti-Müllerian hormone assessment in assisted reproductive technology outcome
AU - Broer, Simone L.
AU - Mol, Benwillem
AU - Dólleman, Madeleine
AU - Fauser, Bart C.
AU - Broekmans, Frank J M
PY - 2010/6/1
Y1 - 2010/6/1
N2 - Purpose of review The purpose of this study is to summarize the role of anti-Müllerian hormone (AMH) in assisted reproductive technology (ART) treatment. Recent findings AMH is a good marker in the prediction of ovarian response to controlled ovarian hyperstimulation. In clinical practice, this means that AMH may be used for identifying poor or excessive responders. So far, studies show that AMH is not a good predictor for the occurrence of pregnancy after ART treatment. Therefore, routine screening for a poor ovarian reserve status using AMH is not to be advocated. Still, ovarian response prediction using AMH may open ways for patient-tailored stimulation protocols in order to reduce cancellations for excessive response, possibly improve pregnancy prospects and reduce costs. Summary AMH is able to predict extremes in ovarian response to controlled ovarian hyperstimulation but cannot predict pregnancy after ART treatment. Its future clinical role may be in the individualization of ART stimulation protocols.
AB - Purpose of review The purpose of this study is to summarize the role of anti-Müllerian hormone (AMH) in assisted reproductive technology (ART) treatment. Recent findings AMH is a good marker in the prediction of ovarian response to controlled ovarian hyperstimulation. In clinical practice, this means that AMH may be used for identifying poor or excessive responders. So far, studies show that AMH is not a good predictor for the occurrence of pregnancy after ART treatment. Therefore, routine screening for a poor ovarian reserve status using AMH is not to be advocated. Still, ovarian response prediction using AMH may open ways for patient-tailored stimulation protocols in order to reduce cancellations for excessive response, possibly improve pregnancy prospects and reduce costs. Summary AMH is able to predict extremes in ovarian response to controlled ovarian hyperstimulation but cannot predict pregnancy after ART treatment. Its future clinical role may be in the individualization of ART stimulation protocols.
KW - Anti-Mudie;llerian hormone
KW - Assisted reproductive technology
KW - In-vitro fertilization
KW - Intracytoplasmic sperm injection
KW - Ovarian response
UR - http://www.scopus.com/inward/record.url?scp=77951938429&partnerID=8YFLogxK
U2 - 10.1097/GCO.0b013e3283384911
DO - 10.1097/GCO.0b013e3283384911
M3 - Review Article
C2 - 20407372
AN - SCOPUS:77951938429
SN - 1040-872X
VL - 22
SP - 193
EP - 201
JO - Current Opinion in Obstetrics and Gynecology
JF - Current Opinion in Obstetrics and Gynecology
IS - 3
ER -