The retinal renin-angiotensin system: roles of angiotensin II and aldosterone

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Abstract

Components of the renina??angiotensin system are expressed in both vascular and neuroglial cells. Angiotensin receptor and ACE blockade reduces vascular and neuroglial injury in retinopathy. A local aldosterone/mineralocorticoid system exists in the retina. Aldosterone may influence vascular pathology and glia and ganglion cell function in the retina.
Original languageEnglish
Pages (from-to)142 - 150
Number of pages9
JournalPeptides
Volume36
Issue number1
DOIs
Publication statusPublished - 2012

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