The retinal renin-angiotensin system: roles of angiotensin II and aldosterone

Jennifer Wilkinson-Berka; Alexander Agrotis; Devy Deliyanti

doi:10.1016/j.peptides.2012.04.008

The retinal renin-angiotensin system: roles of angiotensin II and aldosterone

Jennifer Wilkinson-Berka, Alexander Agrotis, Devy Deliyanti

Immunology Alfred Hospital

Research output: Contribution to journal › Article › Research › peer-review

60 Citations (Scopus)

Abstract

Components of the renina??angiotensin system are expressed in both vascular and neuroglial cells. Angiotensin receptor and ACE blockade reduces vascular and neuroglial injury in retinopathy. A local aldosterone/mineralocorticoid system exists in the retina. Aldosterone may influence vascular pathology and glia and ganglion cell function in the retina.

Original language	English
Pages (from-to)	142 - 150
Number of pages	9
Journal	Peptides
Volume	36
Issue number	1
DOIs	https://doi.org/10.1016/j.peptides.2012.04.008
Publication status	Published - 2012

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10.1016/j.peptides.2012.04.008

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title = "The retinal renin-angiotensin system: roles of angiotensin II and aldosterone",

abstract = "Components of the renina??angiotensin system are expressed in both vascular and neuroglial cells. Angiotensin receptor and ACE blockade reduces vascular and neuroglial injury in retinopathy. A local aldosterone/mineralocorticoid system exists in the retina. Aldosterone may influence vascular pathology and glia and ganglion cell function in the retina.",

author = "Jennifer Wilkinson-Berka and Alexander Agrotis and Devy Deliyanti",

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AU - Wilkinson-Berka, Jennifer

AU - Agrotis, Alexander

AU - Deliyanti, Devy

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N2 - Components of the renina??angiotensin system are expressed in both vascular and neuroglial cells. Angiotensin receptor and ACE blockade reduces vascular and neuroglial injury in retinopathy. A local aldosterone/mineralocorticoid system exists in the retina. Aldosterone may influence vascular pathology and glia and ganglion cell function in the retina.

AB - Components of the renina??angiotensin system are expressed in both vascular and neuroglial cells. Angiotensin receptor and ACE blockade reduces vascular and neuroglial injury in retinopathy. A local aldosterone/mineralocorticoid system exists in the retina. Aldosterone may influence vascular pathology and glia and ganglion cell function in the retina.

UR - http://www.sciencedirect.com/science/article/pii/S0196978112001908#

U2 - 10.1016/j.peptides.2012.04.008

DO - 10.1016/j.peptides.2012.04.008

M3 - Article

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SP - 142

EP - 150

JO - Peptides

JF - Peptides

SN - 0196-9781

IS - 1

ER -

The retinal renin-angiotensin system: roles of angiotensin II and aldosterone

Abstract

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