The Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) Technique Applied to the Study ofMembrane-Active Peptides

Torsten John, Bernd Abel, Lisandra L. Martin

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)


The quartz crystal microbalance with dissipation monitoring (QCM-D) technique is a label-free and highly sensitive approach to study binding events at a sensor surface in real-time. QCM-D is based on the piezoelectric effect where the fundamental frequency of the oscillating quartz sensor is dependent on its mass.
Mass binding to the sensor surface thus causes a measurable frequency decrease (Dmp–Df). The QCM-D technique also enables the measurement of the viscoelasticity and spatial distribution of an adlayer on the sensor surface.
Original languageEnglish
Pages (from-to)543-546
Number of pages4
JournalAustralian Journal of Chemistry
Issue number7
Publication statusPublished - 15 Jun 2018

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