The potential role of nanoyttria in alleviating oxidative stress biomarkers: Implications for Alzheimer's disease therapy

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Abstract

Alzheimer's disease (AD) is a fatal neurodegenerative disease that requires immediate attention. Oxidative stress that leads to the generation of reactive oxygen species is a contributing factor to the disease progression by promoting synthesis and deposition of amyloid-β, the main hallmark protein in AD. It has been previously demonstrated that nanoyttria possesses antioxidant properties and can alleviate cellular oxidative injury in various toxicity and disease models. This review proposed that nanoyttria could be used for the treatment of AD. In this paper, the evidence on the antioxidant potential of nanoyttria is presented and its prospects on AD therapy are discussed.

Original languageEnglish
Article number118287
Number of pages6
JournalLife Sciences
Volume259
DOIs
Publication statusPublished - 15 Oct 2020

Keywords

  • Alzheimer's disease
  • Antioxidants
  • Nanoparticles
  • Oxidative stress
  • Reactive oxygen species
  • Yttria

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