The potential impact of mouse model selection in preclinical evaluation of cancer immunotherapy

Jennifer A Westwood, Phillip K Darcy, Michael H Kershaw

Research output: Contribution to journalLetterOther

5 Citations (Scopus)

Abstract

This commentary provides the authors perspective on the article Routes of delivery for CpG and anti-CD137 for the treatment of orthotopic kidney tumors in mice , published in PLoS ONE. It also discusses the caveats of using subcutaneous tumors to model the treatment of human cancers versus orthotopic mouse models that more closely mimic human disease.
Original languageEnglish
Pages (from-to)1 - 10
Number of pages10
JournalOncoImmunology
Volume3
Issue number7
DOIs
Publication statusPublished - 2014

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