@article{c6d65f4d1e594aed93a4e0a5fe3e0f2d,
title = "The potential for long-term cost-effectiveness of obesity prevention interventions in the early years of life",
abstract = "Background: Early childhood obesity prevention is gaining increasing importance, as the prevalence of children with overweight and obesity aged 5 years and under increases worldwide. Along with understanding the effectiveness of obesity interventions, it is important to understand the cost-effectiveness of interventions over time. Objectives: To estimate the long-term health benefits and health care cost-savings of reductions in BMI for the Australian population of children aged between 2 and 5 years. Methods: A proportional multistate, multiple cohort lifetable model estimated the health benefits and health care cost-savings related to hypothetical reductions in BMI, informed by a scoping review of systematic reviews reporting the effectiveness of obesity prevention interventions in preschool aged children. Results: Results suggest significant potential for cost-effectiveness of obesity prevention interventions in preschool-aged children if intervention effect can be maintained. A relatively small population level reduction in BMI z-score (−0.13 BMIz) in children aged 2 to 5 years would result in 36 496 health-adjusted life years saved (95\% uncertainty interval [UI], 30 283-42 945) and health care cost-savings of approximately \$301 million (95\% UI \$234 million-\$369 million) if modelled over the lifetime. Conclusions: Scenario results highlight the importance of obesity intervention in the early years of life.",
keywords = "cost-effectiveness, health impact modelling, obesity, prevention",
author = "Vicki Brown and Jaithri Ananthapavan and Diana Sonntag and Tan, \{Eng Joo\} and Alison Hayes and Marj Moodie",
note = "Funding Information: National Health and Medical Research Council; Centre for Research Excellence in the Early Prevention of Obesity in Childhood, Grant/ Award Number: APPID1101675; CRE in Obesity Policy and Food Systems, Grant/ Award Number: APPID1041020 Funding Information: Brown, Moodie, Hayes, and Tan are researchers with the National Health and Medical Research Council (NHMRC) funded Centre for Research Excellence (CRE) in the Early Prevention of Obesity in Childhood (APPID1101675). Brown, Ananthapavan, and Moodie are researchers with the NHMRC funded CRE in Obesity Policy and Food Systems (APPID1041020). The opinions, analysis, and conclusions in this paper are those of the author/s and are not necessarily endorsed by the NHMRC. Sonntag gratefully acknowledges salary support from the Excellence Fellowship of the Olympia‐Morata Habilitation Programme, Germany. The authors would like to acknowledge the work of CRE in Obesity Policy and Food Systems collaborators Jan Barendregt, Lennert Veerman, and Ana Maria Mantilla Herrera in development of the CRE‐Obesity Policy model. Funding Information: Brown, Moodie, Hayes, and Tan are researchers with the National Health and Medical Research Council (NHMRC) funded Centre for Research Excellence (CRE) in the Early Prevention of Obesity in Childhood (APPID1101675). Brown, Ananthapavan, and Moodie are researchers with the NHMRC funded CRE in Obesity Policy and Food Systems (APPID1041020). The opinions, analysis, and conclusions in this paper are those of the author/s and are not necessarily endorsed by the NHMRC. Sonntag gratefully acknowledges salary support from the Excellence Fellowship of the Olympia-Morata Habilitation Programme, Germany. The authors would like to acknowledge the work of CRE in Obesity Policy and Food Systems collaborators Jan Barendregt, Lennert Veerman, and Ana Maria Mantilla Herrera in development of the CRE-Obesity Policy model. V.B. and M.M. conceived the study. V.B. and D.S. designed the search strategies, with V.B. undertaking the scoping reviews and extracting data. V.B. conducted the modelling, with J.A. cross-checking modelling assumptions and results. V.B. wrote the first draft of the paper. J.A., D.S., E.T., A.H., and M.M. commented on the paper. Publisher Copyright: {\textcopyright} 2019 World Obesity Federation",
year = "2019",
month = aug,
doi = "10.1111/ijpo.12517",
language = "English",
volume = "14",
journal = "Pediatric Obesity",
issn = "2047-6302",
publisher = "Wiley-Blackwell",
number = "8",
}
