Abstract
Purpose of review As the infant's physiology changes dramatically after birth, modern neonatal resuscitation approaches should detect and be modified in response to these changes. This review describes the changes in respiratory physiology at birth and highlights approaches that can assist these changes. Recent findings To better target assistance given to infants at birth, the changes in lung physiology have been classified into three phases. The first phase involves lung aeration. As little or no gas exchange can occur, assistance should focus on airway liquid clearance. During the second phase, as airway liquid resides in lung tissue, assistance should focus on minimizing the complications associated with lung edema. The third phase occurs whenever the liquid is cleared from the tissue and respiratory mechanics stabilize. Although more traditional approaches are most effective during this phase, this is not the case for the first two phases. Furthermore, the glottis actively adducts during apnea in newborns and so noninvasive respiratory support requires the infant to be breathing so that the glottis will open. Summary The respiratory support provided to infants at birth should match the infant's changing physiology during transition, which requires a more sophisticated approach and equipment than current recommendations.
| Original language | English |
|---|---|
| Pages (from-to) | 187-191 |
| Number of pages | 5 |
| Journal | Current Opinion in Pediatrics |
| Volume | 30 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1 Apr 2018 |
Keywords
- airway liquid clearance
- birth
- preterm birth
- respiratory function
- transient tachynopea of the newborn
Cite this
}
The physiology of neonatal resuscitation. / Hooper, Stuart B.; Kitchen, Marcus J.; Polglase, Graeme R.; Roehr, Charles C.; Te Pas, Arjan B.
In: Current Opinion in Pediatrics, Vol. 30, No. 2, 01.04.2018, p. 187-191.Research output: Contribution to journal › Review Article › Other › peer-review
TY - JOUR
T1 - The physiology of neonatal resuscitation
AU - Hooper, Stuart B.
AU - Kitchen, Marcus J.
AU - Polglase, Graeme R.
AU - Roehr, Charles C.
AU - Te Pas, Arjan B.
PY - 2018/4/1
Y1 - 2018/4/1
N2 - Purpose of review As the infant's physiology changes dramatically after birth, modern neonatal resuscitation approaches should detect and be modified in response to these changes. This review describes the changes in respiratory physiology at birth and highlights approaches that can assist these changes. Recent findings To better target assistance given to infants at birth, the changes in lung physiology have been classified into three phases. The first phase involves lung aeration. As little or no gas exchange can occur, assistance should focus on airway liquid clearance. During the second phase, as airway liquid resides in lung tissue, assistance should focus on minimizing the complications associated with lung edema. The third phase occurs whenever the liquid is cleared from the tissue and respiratory mechanics stabilize. Although more traditional approaches are most effective during this phase, this is not the case for the first two phases. Furthermore, the glottis actively adducts during apnea in newborns and so noninvasive respiratory support requires the infant to be breathing so that the glottis will open. Summary The respiratory support provided to infants at birth should match the infant's changing physiology during transition, which requires a more sophisticated approach and equipment than current recommendations.
AB - Purpose of review As the infant's physiology changes dramatically after birth, modern neonatal resuscitation approaches should detect and be modified in response to these changes. This review describes the changes in respiratory physiology at birth and highlights approaches that can assist these changes. Recent findings To better target assistance given to infants at birth, the changes in lung physiology have been classified into three phases. The first phase involves lung aeration. As little or no gas exchange can occur, assistance should focus on airway liquid clearance. During the second phase, as airway liquid resides in lung tissue, assistance should focus on minimizing the complications associated with lung edema. The third phase occurs whenever the liquid is cleared from the tissue and respiratory mechanics stabilize. Although more traditional approaches are most effective during this phase, this is not the case for the first two phases. Furthermore, the glottis actively adducts during apnea in newborns and so noninvasive respiratory support requires the infant to be breathing so that the glottis will open. Summary The respiratory support provided to infants at birth should match the infant's changing physiology during transition, which requires a more sophisticated approach and equipment than current recommendations.
KW - airway liquid clearance
KW - birth
KW - preterm birth
KW - respiratory function
KW - transient tachynopea of the newborn
UR - http://www.scopus.com/inward/record.url?scp=85044200991&partnerID=8YFLogxK
U2 - 10.1097/MOP.0000000000000590
DO - 10.1097/MOP.0000000000000590
M3 - Review Article
VL - 30
SP - 187
EP - 191
JO - Current Opinion in Pediatrics
JF - Current Opinion in Pediatrics
SN - 1040-8703
IS - 2
ER -