The panorama of pulmonary leiomyoma: A tale of two tumours

Ajit Nair; Paul Leong

doi:10.1002/rcr2.1088

The panorama of pulmonary leiomyoma: A tale of two tumours

Ajit Nair, Paul Leong

Medicine Monash Health

Research output: Contribution to journal › Article › Other › peer-review

Abstract

Pulmonary leiomyoma has a diverse clinical spectrum of disease. Here we describe two patients with vastly different presentations. The first case is a 23-year-old female with a chronic cough and no visible tracheal lesion on computer tomography (CT) chest imaging. Flexible bronchoscopy revealed a small tracheal nodule, with histopathology confirming pulmonary leiomyoma. The second case is a 57-year-old female with a painless abdominal mass. CT imaging revealed widespread lung ‘cannonball’ nodules. Percutaneous biopsy confirmed metastatic leiomyoma. After progression on surveillance and endocrine therapy, she was commenced on doxorubicin with interval radiological improvement. These cases highlight the clinical heterogeneity in this disease, and thus, complexity in devising standardized diagnostic and therapeutic protocols.

Original language	English
Article number	e01088
Number of pages	4
Journal	Respirology Case Reports
Volume	11
Issue number	3
DOIs	https://doi.org/10.1002/rcr2.1088
Publication status	Published - Mar 2023

Keywords

benign metastasizing leiomyoma
bronchoscopy
leiomyosarcoma
lung nodule
primary pulmonary leiomyoma

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abstract = "Pulmonary leiomyoma has a diverse clinical spectrum of disease. Here we describe two patients with vastly different presentations. The first case is a 23-year-old female with a chronic cough and no visible tracheal lesion on computer tomography (CT) chest imaging. Flexible bronchoscopy revealed a small tracheal nodule, with histopathology confirming pulmonary leiomyoma. The second case is a 57-year-old female with a painless abdominal mass. CT imaging revealed widespread lung {\textquoteleft}cannonball{\textquoteright} nodules. Percutaneous biopsy confirmed metastatic leiomyoma. After progression on surveillance and endocrine therapy, she was commenced on doxorubicin with interval radiological improvement. These cases highlight the clinical heterogeneity in this disease, and thus, complexity in devising standardized diagnostic and therapeutic protocols.",

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The panorama of pulmonary leiomyoma: A tale of two tumours

Abstract

Keywords

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