Abstract
In recent years, sheep (Ovis aries) have emerged as a useful animal model for neurological research due to their relatively large brain and blood vessel size, their cortical architecture, and their docile temperament. However, the functional anatomy of sheep brain is not as well studied as that of non-human primates, rodents, and felines. For example, while the location of the sheep motor cortex has been known for many years, there have been few studies of the somatotopy of the motor cortex and there were a range of discrepancies across them. The motivation for this review is to provide a definitive resource for studies of the sheep motor cortex. This work critically reviews the literature examining the organization of the motor cortex in sheep, utilizing studies that have applied direct electrical stimulation and histological methods A clearer understanding of the sheep brain will facilitate and progress the use of this species as a scientific animal model for neurological research.
| Original language | English |
|---|---|
| Pages (from-to) | 306-315 |
| Number of pages | 10 |
| Journal | Neuroscience and Biobehavioral Reviews |
| Volume | 80 |
| DOIs | |
| Publication status | Published - 1 Sep 2017 |
Keywords
- Central pattern generator
- Direct electrical stimulation
- Motor cortex
- Ovine
- Sheep
- Superior frontal gyrus
Cite this
}
The ovine motor cortex : A review of functional mapping and cytoarchitecture. / John, Sam E.; Lovell, Timothy J. H.; Opie, Nicholas L.; Wilson, Stefan; Scordas, Theodore C.; Wong, Yan T.; Rind, Gil S.; Ronayne, Stephen; Bauquier, Sébastien H.; May, Clive N.; Grayden, David B.; O'Brien, Terence J.; Oxley, Thomas J.
In: Neuroscience and Biobehavioral Reviews, Vol. 80, 01.09.2017, p. 306-315.Research output: Contribution to journal › Review Article › Other › peer-review
TY - JOUR
T1 - The ovine motor cortex
T2 - A review of functional mapping and cytoarchitecture
AU - John, Sam E.
AU - Lovell, Timothy J. H.
AU - Opie, Nicholas L.
AU - Wilson, Stefan
AU - Scordas, Theodore C.
AU - Wong, Yan T.
AU - Rind, Gil S.
AU - Ronayne, Stephen
AU - Bauquier, Sébastien H.
AU - May, Clive N.
AU - Grayden, David B.
AU - O'Brien, Terence J.
AU - Oxley, Thomas J.
PY - 2017/9/1
Y1 - 2017/9/1
N2 - In recent years, sheep (Ovis aries) have emerged as a useful animal model for neurological research due to their relatively large brain and blood vessel size, their cortical architecture, and their docile temperament. However, the functional anatomy of sheep brain is not as well studied as that of non-human primates, rodents, and felines. For example, while the location of the sheep motor cortex has been known for many years, there have been few studies of the somatotopy of the motor cortex and there were a range of discrepancies across them. The motivation for this review is to provide a definitive resource for studies of the sheep motor cortex. This work critically reviews the literature examining the organization of the motor cortex in sheep, utilizing studies that have applied direct electrical stimulation and histological methods A clearer understanding of the sheep brain will facilitate and progress the use of this species as a scientific animal model for neurological research.
AB - In recent years, sheep (Ovis aries) have emerged as a useful animal model for neurological research due to their relatively large brain and blood vessel size, their cortical architecture, and their docile temperament. However, the functional anatomy of sheep brain is not as well studied as that of non-human primates, rodents, and felines. For example, while the location of the sheep motor cortex has been known for many years, there have been few studies of the somatotopy of the motor cortex and there were a range of discrepancies across them. The motivation for this review is to provide a definitive resource for studies of the sheep motor cortex. This work critically reviews the literature examining the organization of the motor cortex in sheep, utilizing studies that have applied direct electrical stimulation and histological methods A clearer understanding of the sheep brain will facilitate and progress the use of this species as a scientific animal model for neurological research.
KW - Central pattern generator
KW - Direct electrical stimulation
KW - Motor cortex
KW - Ovine
KW - Sheep
KW - Superior frontal gyrus
UR - http://www.scopus.com/inward/record.url?scp=85020851564&partnerID=8YFLogxK
U2 - 10.1016/j.neubiorev.2017.06.002
DO - 10.1016/j.neubiorev.2017.06.002
M3 - Review Article
VL - 80
SP - 306
EP - 315
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
SN - 0149-7634
ER -