The ovine motor cortex

A review of functional mapping and cytoarchitecture

Sam E. John, Timothy J. H. Lovell, Nicholas L. Opie, Stefan Wilson, Theodore C. Scordas, Yan T. Wong, Gil S. Rind, Stephen Ronayne, Sébastien H. Bauquier, Clive N. May, David B. Grayden, Terence J. O'Brien, Thomas J. Oxley

Research output: Contribution to journalReview ArticleOtherpeer-review

6 Citations (Scopus)

Abstract

In recent years, sheep (Ovis aries) have emerged as a useful animal model for neurological research due to their relatively large brain and blood vessel size, their cortical architecture, and their docile temperament. However, the functional anatomy of sheep brain is not as well studied as that of non-human primates, rodents, and felines. For example, while the location of the sheep motor cortex has been known for many years, there have been few studies of the somatotopy of the motor cortex and there were a range of discrepancies across them. The motivation for this review is to provide a definitive resource for studies of the sheep motor cortex. This work critically reviews the literature examining the organization of the motor cortex in sheep, utilizing studies that have applied direct electrical stimulation and histological methods A clearer understanding of the sheep brain will facilitate and progress the use of this species as a scientific animal model for neurological research.

Original languageEnglish
Pages (from-to)306-315
Number of pages10
JournalNeuroscience and Biobehavioral Reviews
Volume80
DOIs
Publication statusPublished - 1 Sep 2017

Keywords

  • Central pattern generator
  • Direct electrical stimulation
  • Motor cortex
  • Ovine
  • Sheep
  • Superior frontal gyrus

Cite this

John, Sam E. ; Lovell, Timothy J. H. ; Opie, Nicholas L. ; Wilson, Stefan ; Scordas, Theodore C. ; Wong, Yan T. ; Rind, Gil S. ; Ronayne, Stephen ; Bauquier, Sébastien H. ; May, Clive N. ; Grayden, David B. ; O'Brien, Terence J. ; Oxley, Thomas J. / The ovine motor cortex : A review of functional mapping and cytoarchitecture. In: Neuroscience and Biobehavioral Reviews. 2017 ; Vol. 80. pp. 306-315.
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abstract = "In recent years, sheep (Ovis aries) have emerged as a useful animal model for neurological research due to their relatively large brain and blood vessel size, their cortical architecture, and their docile temperament. However, the functional anatomy of sheep brain is not as well studied as that of non-human primates, rodents, and felines. For example, while the location of the sheep motor cortex has been known for many years, there have been few studies of the somatotopy of the motor cortex and there were a range of discrepancies across them. The motivation for this review is to provide a definitive resource for studies of the sheep motor cortex. This work critically reviews the literature examining the organization of the motor cortex in sheep, utilizing studies that have applied direct electrical stimulation and histological methods A clearer understanding of the sheep brain will facilitate and progress the use of this species as a scientific animal model for neurological research.",
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John, SE, Lovell, TJH, Opie, NL, Wilson, S, Scordas, TC, Wong, YT, Rind, GS, Ronayne, S, Bauquier, SH, May, CN, Grayden, DB, O'Brien, TJ & Oxley, TJ 2017, 'The ovine motor cortex: A review of functional mapping and cytoarchitecture', Neuroscience and Biobehavioral Reviews, vol. 80, pp. 306-315. https://doi.org/10.1016/j.neubiorev.2017.06.002

The ovine motor cortex : A review of functional mapping and cytoarchitecture. / John, Sam E.; Lovell, Timothy J. H.; Opie, Nicholas L.; Wilson, Stefan; Scordas, Theodore C.; Wong, Yan T.; Rind, Gil S.; Ronayne, Stephen; Bauquier, Sébastien H.; May, Clive N.; Grayden, David B.; O'Brien, Terence J.; Oxley, Thomas J.

In: Neuroscience and Biobehavioral Reviews, Vol. 80, 01.09.2017, p. 306-315.

Research output: Contribution to journalReview ArticleOtherpeer-review

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