The Nature and Role of Pregnancy-Associated Antigens and the Endocrinology of Early Pregnancy in the Ewe

J. K. Findlay, Mildred Cerini, Marion Sheers, L. D. Staples, I. A. Cumming

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Abstract

Despite descriptions of many of the physiological events of early pregnancy in the ewe, the way in which the immunological and endocrine adjustments are brought about is not well understood. Obviously, specific effects - for example, maintenance of the corpus luteum-are brought about by the presence of a conceptus in the uterus. This has led to a search for substances produced by the conceptus or induced by the presence of the conceptus in the uterus which could be involved in establishing pregnancy. This paper describes the presence in sheep of substances associated with pregnancy and discusses the origin and characterization of these substances and their role in ovine pregnancy.

Original languageEnglish
Title of host publicationMaternal Recognition of Pregnancy
PublisherWiley-Blackwell
Pages239-259
Number of pages21
ISBN (Electronic)9780470720479
ISBN (Print)0444900616, 9780444900616
DOIs
Publication statusPublished - 30 May 2008
Externally publishedYes

Keywords

  • Corpus luteum
  • Endocrinology
  • Immunological adjustments
  • Placental lactogen
  • Pregnancy-associated antigens

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